Islet transplantation: Progress and challenge

被引：40

作者：

Gaglia, JL

Shapiro, AMJ

Weir, GC

机构：

[1] Harvard Univ, Sch Med, Joslin Diabet Ctr, Sect Islet Transplantat & Cell Biol, Boston, MA 02215 USA

[2] Univ Alberta, Clin Islet Transplant Program, Edmonton, AB, Canada

[3] Univ Alberta, Dept Surg, Edmonton, AB, Canada

来源：

ARCHIVES OF MEDICAL RESEARCH | 2005年 / 36卷 / 03期

关键词：

islet transplantation; type; 1; diabetes;

D O I：

10.1016/j.arcmed.2005.03.014

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

For over 30 years, investigators have explored islet transplantation as a logical approach to restoring glucosehomeostasis in persons with diabetes. Islet transplantation can currently provide improved glycemic control, relief from recurrent severe hypoglycemia, and potentially insulin independence. In this review, we describe details of the evolution of modern islet transplantation and provide insight into ongoing clinical and basic research efforts to overcome current obstacles for this promising therapy. (c) 2005 IMSS. Published by Elsevier Inc.

引用

页码：273 / 280

页数：8

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