Current and emerging commercial optical biosensors

被引：138

作者：

Baird, CL ^{[1
]}

Myszka, DG ^{[1
]}

机构：

[1] Univ Utah, Ctr Biomol Interact Anal, Salt Lake City, UT 84132 USA

来源：

JOURNAL OF MOLECULAR RECOGNITION | 2001年 / 14卷 / 05期

关键词：

SPR; evanescent wave; refractometry; protein array; drug discovery;

D O I：

10.1002/jmr.544

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The field of commercial optical biosensors. is rapidly evolving, with new systems and detection methods being developed each year. This review outlines the currently available biosensor hardware and highlights unique features of each platform. Affinity-based biosensor technology, with its high sensitivity, wide versatility and high throughput, is playing a significant role in basic research, pharmaceutical development, and the food and environmental sciences. Likewise, the increasing popularity of biosensors is prompting manufacturers to develop new instrumentation for dedicated applications. We provide a preview of some of the emerging commercial systems that are dedicated to drug discovery, proteomics, clinical diagnostics and routine biomolecular interaction analysis. Copyright (C) 2001 John Wiley & Sons, Ltd.

引用

页码：261 / 268

页数：10

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