Online synonymous codon usage analyses with the ade4 and seqinR packages

被引:75
作者
Charif, D
Thioulouse, J
Lobry, JR
Perrière, G
机构
[1] Univ Lyon 1, Lab Biometrie & Biol Evolut, CNRS, UMR 5558, F-69622 Villeurbanne, France
[2] Univ Lyon 1, INRIA Helix Project, F-69622 Villeurbanne, France
关键词
D O I
10.1093/bioinformatics/bti037
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
: Correspondence analysis of codon usage data is a widely used method in sequence analysis, but the variability in amino acid composition between proteins is a confounding factor when one wants to analyse synonymous codon usage variability. A simple and natural way to cope with this problem is to use within-group correspondence analysis. There is, however, no user-friendly implementation of this method available for genomic studies. Our motivation was to provide to the community a Web facility to easily study synonymous codon usage on a subset of data available in public genomic databases.
引用
收藏
页码:545 / 547
页数:3
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