共 77 条
Optic nerve restoration - New perspectives
被引:11
作者:

Bull, Natalie D.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Cambridge, Ctr Brain Repair, Cambridge CB2 2PY, England Univ Cambridge, Ctr Brain Repair, Cambridge CB2 2PY, England

Martin, Keith R.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Cambridge, Ctr Brain Repair, Cambridge CB2 2PY, England Univ Cambridge, Ctr Brain Repair, Cambridge CB2 2PY, England
机构:
[1] Univ Cambridge, Ctr Brain Repair, Cambridge CB2 2PY, England
关键词:
glaucoma;
stem cells;
Muller cells;
neural repair;
optic nerve;
D O I:
10.1097/IJG.0b013e3180391a18
中图分类号:
R77 [眼科学];
学科分类号:
100212 ;
摘要:
Neural regeneration and repair in the central nervous system are currently hot topics in neuroscience. For many years there has been a hope that neurodegenerative diseases which are resistant to current therapies may be treated by the selective replacement of cells. Yet it is only recently that we have started to acquire the knowledge, tools, and techniques that may translate such optimism into new therapies. In this article, we will consider the potential to restore function to the damaged optic nerve. We will consider the technical issues involved and suggest a strategy for research progress.
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页码:506 / 511
页数:6
相关论文
共 77 条
[1]
GROWTH AND CONNECTIVITY OF AXOTOMIZED RETINAL NEURONS IN ADULT-RATS WITH OPTIC NERVES SUBSTITUTED BY PNS GRAFTS LINKING THE EYE AND THE MIDBRAIN
[J].
AGUAYO, AJ
;
VIDALSANZ, M
;
VILLEGASPEREZ, MP
;
BRAY, GM
.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES,
1987, 495
:1-9

AGUAYO, AJ
论文数: 0 引用数: 0
h-index: 0
机构:
MCGILL UNIV,MONTREAL H3A 2T5,QUEBEC,CANADA MCGILL UNIV,MONTREAL H3A 2T5,QUEBEC,CANADA

VIDALSANZ, M
论文数: 0 引用数: 0
h-index: 0
机构:
MCGILL UNIV,MONTREAL H3A 2T5,QUEBEC,CANADA MCGILL UNIV,MONTREAL H3A 2T5,QUEBEC,CANADA

VILLEGASPEREZ, MP
论文数: 0 引用数: 0
h-index: 0
机构:
MCGILL UNIV,MONTREAL H3A 2T5,QUEBEC,CANADA MCGILL UNIV,MONTREAL H3A 2T5,QUEBEC,CANADA

BRAY, GM
论文数: 0 引用数: 0
h-index: 0
机构:
MCGILL UNIV,MONTREAL H3A 2T5,QUEBEC,CANADA MCGILL UNIV,MONTREAL H3A 2T5,QUEBEC,CANADA
[2]
Transplanted glial scar impedes olfactory bulb reinnervation
[J].
Anders, JJ
;
Hurlock, JA
.
EXPERIMENTAL NEUROLOGY,
1996, 142 (01)
:144-150

Anders, JJ
论文数: 0 引用数: 0
h-index: 0
机构:
BAYLOR COLL MED,DEPT PEDIAT,HOUSTON,TX 77030 BAYLOR COLL MED,DEPT PEDIAT,HOUSTON,TX 77030

Hurlock, JA
论文数: 0 引用数: 0
h-index: 0
机构:
BAYLOR COLL MED,DEPT PEDIAT,HOUSTON,TX 77030 BAYLOR COLL MED,DEPT PEDIAT,HOUSTON,TX 77030
[3]
Neurally selected embryonic stem cells induce tumor formation after long-term survival following engraftment into the subretinal space
[J].
Arnhold, S
;
Klein, H
;
Semkova, I
;
Addicks, K
;
Schraermeyer, U
.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,
2004, 45 (12)
:4251-4255

Arnhold, S
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cologne, Dept Anat 1, D-50931 Cologne, Germany

Klein, H
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cologne, Dept Anat 1, D-50931 Cologne, Germany

Semkova, I
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cologne, Dept Anat 1, D-50931 Cologne, Germany

Addicks, K
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cologne, Dept Anat 1, D-50931 Cologne, Germany

Schraermeyer, U
论文数: 0 引用数: 0
h-index: 0
机构: Univ Cologne, Dept Anat 1, D-50931 Cologne, Germany
[4]
Retinal incorporation and differentiation of neural precursors derived from human embryonic stem cells
[J].
Banin, Eyal
;
Obolensky, Alexey
;
Idelson, Maria
;
Hemo, Itzhak
;
Reinhardtz, Etti
;
Pikarsky, Eli
;
Ben-Hur, Tamir
;
Reubinoff, Benjamin
.
STEM CELLS,
2006, 24 (02)
:246-257

Banin, Eyal
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Ophthalmol, Hadassah Human Embryon Stem Cell Res Ctr,Goldyne, Jerusalem, Israel

Obolensky, Alexey
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Ophthalmol, Hadassah Human Embryon Stem Cell Res Ctr,Goldyne, Jerusalem, Israel

Idelson, Maria
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Ophthalmol, Hadassah Human Embryon Stem Cell Res Ctr,Goldyne, Jerusalem, Israel

Hemo, Itzhak
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Ophthalmol, Hadassah Human Embryon Stem Cell Res Ctr,Goldyne, Jerusalem, Israel

Reinhardtz, Etti
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Ophthalmol, Hadassah Human Embryon Stem Cell Res Ctr,Goldyne, Jerusalem, Israel

Pikarsky, Eli
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Ophthalmol, Hadassah Human Embryon Stem Cell Res Ctr,Goldyne, Jerusalem, Israel

Ben-Hur, Tamir
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Ophthalmol, Hadassah Human Embryon Stem Cell Res Ctr,Goldyne, Jerusalem, Israel

Reubinoff, Benjamin
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Ophthalmol, Hadassah Human Embryon Stem Cell Res Ctr,Goldyne, Jerusalem, Israel
[5]
Chemokines regulate the migration of neural progenitors to sites of neuroinflammation
[J].
Belmadani, A
;
Tran, PB
;
Ren, DJ
;
Miller, RJ
.
JOURNAL OF NEUROSCIENCE,
2006, 26 (12)
:3182-3191

Belmadani, A
论文数: 0 引用数: 0
h-index: 0
机构:
Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA

Tran, PB
论文数: 0 引用数: 0
h-index: 0
机构:
Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA

Ren, DJ
论文数: 0 引用数: 0
h-index: 0
机构:
Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA

Miller, RJ
论文数: 0 引用数: 0
h-index: 0
机构:
Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA
[6]
Pattern electroretinography in a rat model of ocular hypertension: functional evidence for early detection of inner retinal damage
[J].
Ben-Shlomo, G
;
Bakalash, S
;
Lambrou, GN
;
Latour, E
;
Dawson, WW
;
Schwartz, M
;
Ofri, R
.
EXPERIMENTAL EYE RESEARCH,
2005, 81 (03)
:340-349

Ben-Shlomo, G
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Koret Sch Vet Med, IL-76100 Rehovot, Israel

Bakalash, S
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Koret Sch Vet Med, IL-76100 Rehovot, Israel

Lambrou, GN
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Koret Sch Vet Med, IL-76100 Rehovot, Israel

Latour, E
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Koret Sch Vet Med, IL-76100 Rehovot, Israel

Dawson, WW
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Koret Sch Vet Med, IL-76100 Rehovot, Israel

论文数: 引用数:
h-index:
机构:

Ofri, R
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Koret Sch Vet Med, IL-76100 Rehovot, Israel
[7]
Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants
[J].
Bieberich, E
;
Silva, J
;
Wang, GH
;
Krishnamurthy, K
;
Condie, BG
.
JOURNAL OF CELL BIOLOGY,
2004, 167 (04)
:723-734

Bieberich, E
论文数: 0 引用数: 0
h-index: 0
机构:
Med Coll Georgia, Sch Med, Inst Mol Med & Genet, Augusta, GA 30912 USA Med Coll Georgia, Sch Med, Inst Mol Med & Genet, Augusta, GA 30912 USA

Silva, J
论文数: 0 引用数: 0
h-index: 0
机构: Med Coll Georgia, Sch Med, Inst Mol Med & Genet, Augusta, GA 30912 USA

Wang, GH
论文数: 0 引用数: 0
h-index: 0
机构: Med Coll Georgia, Sch Med, Inst Mol Med & Genet, Augusta, GA 30912 USA

Krishnamurthy, K
论文数: 0 引用数: 0
h-index: 0
机构: Med Coll Georgia, Sch Med, Inst Mol Med & Genet, Augusta, GA 30912 USA

Condie, BG
论文数: 0 引用数: 0
h-index: 0
机构: Med Coll Georgia, Sch Med, Inst Mol Med & Genet, Augusta, GA 30912 USA
[8]
Role of complement in neurodegeneration and neuroinflammation
[J].
Bonifati, Domenico Marco
;
Kishore, Uday
.
MOLECULAR IMMUNOLOGY,
2007, 44 (05)
:999-1010

Bonifati, Domenico Marco
论文数: 0 引用数: 0
h-index: 0
机构: Univ Padua, Dept Neurosci, Neurol Clin 2, Padua, Italy

Kishore, Uday
论文数: 0 引用数: 0
h-index: 0
机构: Univ Padua, Dept Neurosci, Neurol Clin 2, Padua, Italy
[9]
Chondroitinase ABC promotes functional recovery after spinal cord injury
[J].
Bradbury, EJ
;
Moon, LDF
;
Popat, RJ
;
King, VR
;
Bennett, GS
;
Patel, PN
;
Fawcett, JW
;
McMahon, SB
.
NATURE,
2002, 416 (6881)
:636-640

Bradbury, EJ
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Ctr Res Neurosci, Sensory Funct Grp, London SE1 1UL, England

Moon, LDF
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Ctr Res Neurosci, Sensory Funct Grp, London SE1 1UL, England

Popat, RJ
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Ctr Res Neurosci, Sensory Funct Grp, London SE1 1UL, England

King, VR
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Ctr Res Neurosci, Sensory Funct Grp, London SE1 1UL, England

Bennett, GS
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Ctr Res Neurosci, Sensory Funct Grp, London SE1 1UL, England

Patel, PN
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Ctr Res Neurosci, Sensory Funct Grp, London SE1 1UL, England

Fawcett, JW
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Ctr Res Neurosci, Sensory Funct Grp, London SE1 1UL, England

McMahon, SB
论文数: 0 引用数: 0
h-index: 0
机构: Kings Coll London, Ctr Res Neurosci, Sensory Funct Grp, London SE1 1UL, England
[10]
The origin and efficient derivation of embryonic stem cells in the mouse
[J].
Brook, FA
;
Gardner, RL
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
1997, 94 (11)
:5709-5712

Brook, FA
论文数: 0 引用数: 0
h-index: 0
机构: Department of Zoology, University of Oxford, Oxford, OX1 3PS, South Parks Road

Gardner, RL
论文数: 0 引用数: 0
h-index: 0
机构: Department of Zoology, University of Oxford, Oxford, OX1 3PS, South Parks Road