The revolution of cosmeceuticals delivery by using nanotechnology: A narrative review of advantages and side effects

被引:39
作者
Abu Hajleh, Maha N. [1 ]
Abu-Huwaij, Rana [2 ]
AL-Samydai, Ali [2 ]
Al-Halaseh, Lidia Kamal [3 ]
Al-Dujaili, Emad A. [4 ]
机构
[1] Al Ahliyya Amman Univ, Fac Allied Med Sci, Dept Cosmet Sci, Pharmacol & Diagnost Res Ctr, Amman 19328, Jordan
[2] Al Ahliyya Amman Univ, Pharmacol & Diagnost Res Ctr, Fac Pharm, Amman, Jordan
[3] Mutah Univ, Dept Pharmaceut Chem, Fac Pharm, Al Karak, Jordan
[4] Univ Edinburgh, Ctr Cardiovasc Sci, Queens Med Res Inst, Edinburgh, Midlothian, Scotland
关键词
cosmeceuticals; delivery system; nanocarriers; nanocosmeceuticals; nanostructure; nanotechnology; SOLID LIPID NANOPARTICLES; POORLY SOLUBLE DRUGS; IN-VITRO EVALUATION; GOLD NANOPARTICLES; DERMAL DELIVERY; SKIN; NANOEMULSIONS; TOXICITY; NLC; NANOMATERIALS;
D O I
10.1111/jocd.14441
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100227 [皮肤病学];
摘要
Background The qualified and paradigm jump in the formulation and production of cosmeceuticals refer in some way to the great revolution in nanotechnology. Nowadays, the industry of nano-formulated cosmeceuticals plays a significant and essential role in the evolution and growth of the pharmaceutical industries. This review manuscript focuses on the use of nanocarriers in delivering the cosmetic agents into the target area such as skin, hair, and nails. Methods Many steps were performed in the preparation of this review including identification of different classes of nanocarriers for delivery of nanocosmeceuticals, literature survey of relevantstudies regarding the applications of nanotechnology in cosmeceuticals and their toxicological effects. Results When nanoparticles introduced in the cosmetic industry, the quality and the elegance of the final products were raised significantly. Sadly, this revolution is accompanied by many health hazards as these tiny molecules can penetrate intact skin barriers and cause undesired effects. Cosmeceuticals with nanotechnology include sunscreens, hair cleansing products, nail products, and agents fighting fine lines. Conclusions The expansion and growth of the cosmetic industry and the introduction of nanotechnology in cosmeceuticals industry necessitates the urgent need for scientific research investigating their efficacy, safety profile and use.
引用
收藏
页码:3818 / 3828
页数:11
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