Prevalence of silent myocardial ischemia in persons with diabetes mellitus or impaired glucose tolerance and association of hemoglobin A1c with prevalence of silent myocardial ischemia

被引:20
作者
Deluca, AJ [1 ]
Saulle, LN [1 ]
Aronow, WS [1 ]
Ravipati, G [1 ]
Weiss, MB [1 ]
机构
[1] New York Med Coll, Dept Med, Div Cardiol, Valhalla, NY 10595 USA
关键词
D O I
10.1016/j.amjcard.2005.02.016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Silent myocardial ischemia detected by exercise treadmill or pharmacologic sestamibi stress testing was present in 67 of 196 patients (34%) who had diabetes mellitus or impaired glucose tolerance and in 89 of 640 patients (14%) who had normal glucose tolerance (p < 0.001). Among those who had diabetes mellitus or impaired glucose tolerance, silent myocardial ischemia was present in 27 of 54 patients (50%) who had a hemoglobin A(1c) level >= 7.6% and in 39 of 137 patients (28%) with a hemoglobin A(1c) level < 7.6%(p < 0.005). (c) 2005 by Excerpta Medica Inc.
引用
收藏
页码:1472 / 1474
页数:3
相关论文
共 8 条
[1]   Prevalence and prognostic value of perfusion defects detected by stress technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography in asymptomatic patients with, diabetes mellitus and no known coronary artery disease [J].
De Lorenzo, A ;
Lima, RSL ;
Siqueira, AG ;
Pantoja, MR .
AMERICAN JOURNAL OF CARDIOLOGY, 2002, 90 (08) :827-832
[2]  
Faglia E, 1997, AM J CARDIOL, V79, P134
[3]   Silent myocardial ischemia in patients with diabetes - who to screen [J].
Janand-Delenne, B ;
Savin, B ;
Habib, G ;
Bory, M ;
Vague, P ;
Lassmann-Vague, V .
DIABETES CARE, 1999, 22 (09) :1396-1400
[4]   Association of hemoglobin A1c with cardiovascular disease and mortality in adults:: The European prospective investigation into cancer in Norfolk [J].
Khaw, KT ;
Wareham, N ;
Bingham, S ;
Luben, R ;
Welch, A ;
Day, N .
ANNALS OF INTERNAL MEDICINE, 2004, 141 (06) :413-420
[5]   SILENT-MYOCARDIAL-ISCHEMIA IN PATIENTS WITH NON-INSULIN-DEPENDENT DIABETES-MELLITUS AS JUDGED BY TREADMILL EXERCISE TESTING AND CORONARY ANGIOGRAPHY [J].
NAKA, M ;
HIRAMATSU, K ;
AIZAWA, T ;
MOMOSE, A ;
YOSHIZAWA, K ;
SHIGEMATSU, S ;
ISHIHARA, F ;
NIWA, A ;
YAMADA, T .
AMERICAN HEART JOURNAL, 1992, 123 (01) :46-53
[6]   Diabetes mellitus in older African-Americans, Hispanics, and whites in an academic hospital-based geriatrics practice [J].
Ness, J ;
Nassimiha, D ;
Feria, MI ;
Aronow, WS .
CORONARY ARTERY DISEASE, 1999, 10 (05) :343-346
[7]  
Stemmer Edward A., 1997, P199
[8]   Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study [J].
Wackers, FJT ;
Young, LH ;
Inzucchi, SE ;
Chyun, DA ;
Davey, JA ;
Barrett, EJ ;
Taillefer, R ;
Wittlin, SD ;
Heller, GV ;
Filipchuk, N ;
Engel, S ;
Ratner, RE ;
Iskandrian, AE .
DIABETES CARE, 2004, 27 (08) :1954-1961