Sociodemographic Correlates of Cognition in the Multi-Ethnic Study of Atherosclerosis (MESA)

被引：54

作者：

Fitzpatrick, Annette L. ^{[1
,2
,3
]}

Rapp, Stephen R. ^{[4
]}

Luchsinger, Jose ^{[5
,6
]}

Hill-Briggs, Felicia ^{[7
,8
]}

Alonso, Alvaro ^{[9
]}

Gottesman, Rebecca ^{[10
]}

Lee, Hochang ^{[11
]}

Carnethon, Mercedes ^{[12
]}

Liu, Kiang ^{[12
]}

Williams, Kayleen ^{[13
]}

Sharrett, A. Richey ^{[14
]}

Frazier-Wood, Alexis ^{[15
]}

Lyketsos, Constantine ^{[16
]}

Seeman, Teresa ^{[17
,18
]}

机构：

[1] Univ Washington, Dept Family Med, Seattle, WA 98195 USA

[2] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

[3] Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA

[4] Wake Forest Univ, Bowman Gray Sch Med, Dept Psychiat & Behav Med, Winston Salem, NC USA

[5] Columbia Univ, Dept Med, Med Ctr, New York, NY USA

[6] Columbia Univ, Med Ctr, Dept Epidemiol, New York, NY USA

[7] Johns Hopkins Med Inst, Dept Med, Baltimore, MD 21205 USA

[8] Johns Hopkins Med Inst, Dept Hlth Behav & Soc, Baltimore, MD 21205 USA

[9] Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA

[10] Johns Hopkins Univ Hosp, Dept Cerebrovasc Neurol, Baltimore, MD 21287 USA

[11] Yale Univ, Sch Med, Psychol Med Serv, New Haven, CT USA

[12] Northwestern Univ, Feinberg Sch Med, Dept Prevent Med, Chicago, IL 60611 USA

[13] Univ Washington, Dept Biostat, Seattle, WA 98195 USA

[14] Johns Hopkins Univ, Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

[15] Baylor Coll Med, USDA ARS Childrens Nutr Res Ctr, Houston, TX 77030 USA

[16] Johns Hopkins Univ, Dept Psychiat & Behav Sci, Baltimore, MD USA

[17] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90024 USA

[18] Univ Calif Los Angeles, Dept Epidemiol, Los Angeles, CA 90024 USA

来源：

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY | 2015年 / 23卷 / 07期

关键词：

MESA; cognition; methods; multi-ethnic; race; socioeconomic; AFRICAN-AMERICANS; KING COUNTY; DEMENTIA; EDUCATION; PERFORMANCE; PREVALENCE; CULTURE; DECLINE; MEMORY; RACE;

D O I：

10.1016/j.jagp.2015.01.003

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Objective: To describe the methodology utilized to evaluate cognitive function in the Multi-Ethnic Study of Atherosclerosis (MESA) and to present preliminary results by age, sex, and race/ethnicity. Design: Cross-sectional measurements of a prospective observational cohort. Setting: Residents of 6 U.S. communities free of cardiovascular disease at baseline (2000-02). Participants: 4,591 adults who completed the fifth MESA clinical examination in 2011-12; mean age 70.3 (SD: 9.5) years, 53.1% women, 40.7% non-Hispanic white, 26.4% non-Hispanic black, 21.4% Hispanic, and 11.5% Chinese. Measurements: The cognitive battery consisted of the Cognitive Abilities Screening Instrument (version 2) to evaluate global cognition, the Digit Symbol Code for processing speed and Digit Spans Forward and Backward to assess memory. Demographic, socioeconomic, and cultural covariates were also collected for descriptive statistics and multivariate modeling. Results: Associations between socioeconomic factors and cognition revealed that age, race/ethnicity, education, occupational status, household income, health insurance type, household size, place of birth, years and generation in U.S., and the presence of the ApoE4 allele were significantly associated with performance on the cognitive tests, although patterns varied by specific test, racial/ethnicity, and sociocultural factors. Conclusion: As many of the influencing cultural and socioeconomic factors measured here are complex, multifactorial, and may not be adequately quantified, caution has been

引用

页码：684 / 697

页数：14

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