Cleavage furrow positioning

被引：85

作者：

Glotzer, M ^{[1
]}

机构：

[1] Res Inst Mol Pathol, A-1030 Vienna, Austria

来源：

JOURNAL OF CELL BIOLOGY | 2004年 / 164卷 / 03期

关键词：

cytokinesis; Rho; microtubule; kinesin; actin;

D O I：

10.1083/jcb.200310112

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

To complete the cell cycle, the cleavage furrow draws the plasma membrane toward the cell center, pinching the cytoplasm into two lobes that are subsequently separated into two cells. The position of the cleavage furrow is induced by the mitotic spindle during early anaphase. Although the mechanism of cleavage furrow positioning is not understood at a molecular level, recent results suggest that it might be mediated by local relief from the inhibitory effects of microtubules.

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收藏

页码：347 / 351

页数：5

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