Increasing resistance of M-tuberculosis to anti-TB drugs in Saudi Arabia

被引：40

作者：

Khan, MY

Kinsara, AJ

Osoba, AO

Wali, S

Samman, Y

Memish, Z

机构：

[1] King Fahad Natl Guard Hosp, Riyadh 11426, Saudi Arabia

[2] King Khalid Natl Guard Hosp, Jeddah, Saudi Arabia

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2001年 / 17卷 / 05期

关键词：

Mycobacterium tuberculosis; Saudi Arabia; tuberculosis; antimicrobial resistance;

D O I：

10.1016/S0924-8579(01)00298-9

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The incidence of drug resistance in Mycobacterium tuberculosis (MTB) isolated from our hospital between April 1996 and March 1998 was compared with an earlier study (1993-1995). Thirty (29.7%) of 101 MTB isolates were resistant to one or more anti-TB drugs and 21 (20%) of 101 were multi-drug resistant M. tuberculosis (MDR-TB). Resistance was most common to isoniazid (28.7%), followed by streptomycin (22.8%) and rifampicin (20.8%). Resistance to pyrazinamide and ethambutol was 7.9 and 6.9%, respectively. There was a three-fold increase in resistance compared with the earlier study. (C) 2001 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.

引用

页码：415 / 418

页数：4

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