Bioactive chemical constituents from Alchornea laxiflora (benth) pax and hoffman

被引：40

作者：

Ogundipe, OO

Moody, JO ^{[1
]}

Houghton, PJ

Odelola, HA

机构：

[1] Univ Ibadan, Fac Pharm, Dept Pharmacognosy, Ibadan, Nigeria

[2] Kings Coll London, Dept Pharmacognosy, London SE1 8WA, England

[3] Univ Ibadan, Dept Pharmaceut Microbiol & Clin Pharm, Ibadan, Nigeria

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2001年 / 74卷 / 03期

关键词：

Alchornea laxiflora; Euphorbiaceae; chemical constituents; biological activity;

D O I：

10.1016/S0378-8741(00)00352-4

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Quercetin-7,4'-disulphate (1) quercetin (2) quercetin-3',4'-disuIphate (3) quercetin-3,4'-diacetate (4) rutin (5) and quercetrin (6) were isolated from the ethyl acetate soluble fraction (ESM) of the crude methanolic leaf extract of Alchornea laxiflora. Purification of these compounds was carried out by column chromatography utilising sephadex LH 20 and various mixtures of water, methanol, ethanol and toluene as eluents. Structural elucidation was by UV, IR,(HNMR)-H-1 and (CNMR)-C-13 spectroscopy as well as by FAB-MS. Antimicrobial activity of isolated compounds was detected in Gram-positive, Gram-negative and fungal organisms. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：275 / 280

页数：6

共 12 条

[1]

Adewole AA., 1993, COMMUNICATION

[2]

AN EQUIMOLAR MIXTURE OF QUERCETIN 3-SULFATE AND PATULETIN 3-SULFATE FROM FLAVERIA-CHLORAEFOLIA [J].