Cellular injury score for multiple organ failure severity scoring system

被引：22

作者：

Oda, S ^{[1
]}

Hirasawa, H ^{[1
]}

Sugai, T ^{[1
]}

Shiga, H ^{[1
]}

Matsuda, K ^{[1
]}

Ueno, H ^{[1
]}

机构：

[1] Chiba Univ, Sch Med, Dept Emergency & Crit Care Med, Chuo Ku, Chiba 260, Japan

来源：

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE | 1998年 / 45卷 / 02期

关键词：

multiple organ failure; severity scoring system; mortality risk prediction; cellular injury score; arterial ketone body ratio; osmolality gap;

D O I：

10.1097/00005373-199808000-00016

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Background: Cellular Injury Score (CIS) is an index of cellular injury, being calculated from three parameters of intra cellular metabolism: arterial ketone body ratio, osmolality gap, and blood lactate. Methods: The usefulness of CIS as a severity scoring system for patients with multiple organ failure was prospectively evaluated in 157 consecutive patients with MOF (58 survivors, 99 nonsurvivors). Results: CISs in nonsurvivors were significantly higher compared with those in survivors throughout the clinical courses. CIS was significantly correlated with the number of failing organs and mortality rate. The optimal cutoff point of CIS from receiver operating characteristics curve analysis was 4 for the maximal value during the clinical course, The changes in CIS well reflected the severity of injury in survivors and nonsurvivors who died within 2 weeks. Conclusion: CIS could be a useful index for mortality risk prediction and is potentially applicable as a severity scoring system for individual patients with MOF.

引用

页码：304 / 310

页数：7

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