TGF-β signalling pathways in early Xenopus development

被引：78

作者：

Hill, CS ^{[1
]}

机构：

[1] Imperial Canc Res Fund, Lab Dev Signalling, London WC2A 3PX, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2001年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(00)00229-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

Many different ligands of the TGF-beta superfamily signal in the early Xenopus embryo and are required for the specification and patterning of the three germ layers as well as for gastrulation. Recent advances in the field are helping us understand how ligand activity is regulated both spatially and temporally, the mechanism by which the signals are transduced to the nucleus and how essentially the same signalling pathway can activate completely different sets of genes in different regions of the embryo.

引用

页码：533 / 540

页数：8

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