Effects of acute and chronic physical exercise and stress on different types of memory in rats

被引：52

作者：

Mello, Pamela Billig ^{[1
,2
]}

Benetti, Fernando ^{[1
,2
]}

Cammarota, Martin ^{[1
]}

Izquierdo, Ivan ^{[1
]}

机构：

[1] Pontificia Univ Catolica Rio Grande do Sul, Ctr Memoria, Inst Pesquisas Biomed, BR-90610000 Porto Alegre, RS, Brazil

[2] Univ Fed Rio Grande do Sul, Programa Posgrad Ciencias Biol Fisiol, Inst Ciencias Bas Saude, BR-90050170 Porto Alegre, RS, Brazil

来源：

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS | 2008年 / 80卷 / 02期

关键词：

physical activity; stress; learning and memory; forced running;

D O I：

10.1590/S0001-37652008000200008

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Here we study the effect of acute and chronic physical exercise in a treadmill and of daily stress ( because forced exercise involves a degree of stress) during 2 or 8 weeks on different types of memory in male Wistar rats. The memory tests employed were: habituation in an open field, object recognition and spatial learning in the Morris water maze. Daily foot-shock stress enhanced habituation learning after 2 but not after 8 weeks; it hindered both short-(STM) and long-term memory (LTM) of the recognition task at 2 weeks but only STM after 8 weeks and had no effect on spatial learning after either 2 or 8 weeks. Acute but not chronic exercise also enhanced habituation in the open field and hindered STM and LTM in the recognition task. Chronic exercise enhanced one important measure of spatial learning ( latency to escape) but not others. Our findings indicate that some care must be taken when interpreting effects of forced exercise on brain parameters since at least part of them may be due to the stress inherent to the training procedure.

引用

页码：301 / 309

页数：9

共 41 条

[31] Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress [J].