Pathogenesis and management of hepatorenal syndrome in patients with cirrhosis

被引：68

作者：

Angeli, Paolo ^{[1
]}

Merkel, Carlo ^{[1
]}

机构：

[1] Univ Padua, Dept Clin & Expt Med, I-35126 Padua, Italy

来源：

JOURNAL OF HEPATOLOGY | 2008年 / 48卷

关键词：

renal failure; vasoconstrictors; human albumin; terlipressin;

D O I：

10.1016/j.jhep.2008.01.010

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatorenal syndrome is a severe complication of advanced liver cirrhosis, in patients with ascites and marked circulatory dysfunction. It is clearly established that it has a functional nature, and that it is related to intense renal vasoconstriction. Despite its functional origin, the prognosis is very poor. In the present review, the most recent advances in diagnosis, pathophysiology, and treatment are discussed. Recent developments in pathophysiology are the basis of the new therapeutic strategies, which are currently under evaluation in randomised clinical trials. (c) 2008 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

引用

页码：S93 / S103

页数：11

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