Neural Progenitor Cell Polarity and Cortical Development

被引：77

作者：

Arai, Yoko ^{[1
]}

Taverna, Elena ^{[2
]}

机构：

[1] PSL Res Univ, CIRB, Coll France, CNRS UMR 7241,INSERM U1050, Paris, France

[2] Max Planck Inst Evolutionary Anthropol MPG, Dept Evolutionary Genet, Leipzig, Germany

来源：

FRONTIERS IN CELLULAR NEUROSCIENCE | 2017年 / 11卷

关键词：

brain development; epithelial polarity; apical progenitors; basal progenitors; neural stem and progenitor cells; polarity; epithelial to mesenchymal transition (EMT); neurodevelopmental disorders; OUTER SUBVENTRICULAR ZONE; INTERKINETIC NUCLEAR MIGRATION; DEVELOPING CEREBRAL-CORTEX; FIBROBLAST-GROWTH-FACTOR; MESSENGER-RNA TRANSPORT; RADIAL GLIA; NEUROEPITHELIAL CELLS; EMBRYONIC NEOCORTEX; STEM-CELLS; MAMMALIAN TELENCEPHALON;

D O I：

10.3389/fncel.2017.00384

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Neurons populating the cerebral cortex are generated during embryonic development from neural stem and progenitor cells in a process called neurogenesis. Neural stem and progenitor cells are classified into several classes based on the different location of mitosis (apical or basal) and polarity features (bipolar, monopolar and non-polar). The polarized architecture of stem cells is linked to the asymmetric localization of proteins, mRNAs and organelles, such as the centrosome and the Golgi apparatus (GA). Polarity affects stem cell function and allows stem cells to integrate environmental cues from distinct niches in the developing cerebral cortex. The crucial role of polarity in neural stem and progenitor cells is highlighted by the fact that impairment of cell polarity is linked to neurodevelopmental disorders such as Down syndrome, Fragile X syndrome, autism spectrum disorders (ASD) and schizophrenia.

引用

页数：11

共 107 条

[1]

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease [J].

Acloque, Herve ;

Adams, Meghan S. ;

Fishwick, Katherine ;

Bronner-Fraser, Marianne ;

Angela Nieto, M. .

JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (06) :1438-1449

[2]

A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels [J].

Angeles Martinez-Martinez, Maria ;

De Juan Romero, Camino ;

Fernandez, Virginia ;

Cardenas, Adrian ;

Goetz, Magdalena ;

Borrell, Victor .

NATURE COMMUNICATIONS, 2016, 7

[3]

Development and evolution of cortical fields [J].

Arai, Yoko ;

Pierani, Alessandra .

NEUROSCIENCE RESEARCH, 2014, 86 :66-76

[4]

Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics [J].

Bagni, Claudia ;

Tassone, Flora ;

Neri, Giovanni ;

Hagerman, Randi .

JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (12) :4314-4322

[5]

Precursor Diversity and Complexity of Lineage Relationships in the Outer Subventricular Zone of the Primate [J].

Betizeau, Marion ;

Cortay, Veronique ;

Patti, Dorothee ;

Pfister, Sabina ;

Gautier, Elodie ;

Bellemin-Menard, Angele ;

Afanassieff, Marielle ;

Huissoud, Cyril ;

Douglas, Rodney J. ;

Kennedy, Henry ;

Dehay, Colette .

NEURON, 2013, 80 (02) :442-457

[6]

Prenatal Expression Patterns of Genes Associated With Neuropsychiatric Disorders [J].

Birnbaum, Rebecca ;

Jaffe, Andrew E. ;

Hyde, Thomas M. ;

Kleinman, Joel E. ;

Weinberger, Daniel R. .

AMERICAN JOURNAL OF PSYCHIATRY, 2014, 171 (07) :758-767

[7]

ASPM is a major determinant of cerebral cortical size [J].

Bond, J ;

Roberts, E ;

Mochida, GH ;

Hampshire, DJ ;

Scott, S ;

Askham, JM ;

Springell, K ;

Mahadevan, M ;

Crow, YJ ;

Markham, AF ;

Walsh, CA ;

Woods, CG .

NATURE GENETICS, 2002, 32 (02) :316-320

[8]

Dendritic mRNA: transport, translation and function [J].

Bramham, Clive R. ;

Wells, David G. .

NATURE REVIEWS NEUROSCIENCE, 2007, 8 (10) :776-789

[9]

Heads-Up: New Roles for the Fragile X Mental Retardation Protein in Neural Stem and Progenitor Cells [J].

Callan, Matthew A. ;

Zarnescu, Daniela C. .

GENESIS, 2011, 49 (06) :424-440

[10]

Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome [J].

Cantagrel, Vincent ;

Silhavy, Jennifer L. ;

Bielas, Stephanie L. ;

Swistun, Dominika ;

Marsh, Sarah E. ;

Bertrand, Julien Y. ;

Audollent, Sophie ;

Attie-Bitach, Tania ;

Holden, Kenton R. ;

Dobyns, William B. ;

Traver, David ;

Al-Gazali, Lihadh ;

Ali, Bassam R. ;

Lindner, Tom H. ;

Caspary, Tamara ;

Otto, Edgar A. ;

Hildebrandt, Friedhelm ;

Glass, Ian A. ;

Logan, Clare V. ;

Johnson, Colin A. ;

Bennett, Christopher ;

Brancati, Francesco ;

Valente, Enza Maria ;

Woods, C. Geoffrey ;

Gleeson, Joseph G. .

AMERICAN JOURNAL OF HUMAN GENETICS, 2008, 83 (02) :170-179

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