Ferric chloride hexahydrate: A convenient reagent for the oxidation of Hantzsch 1,4-dihydropyridines

被引：43

作者：

Lu, J ^{[1
]}

Bai, YJ

Wang, ZJ

Yang, BQ

Li, WH

机构：

[1] NW Univ Xian, Dept Chem, Xian 710069, Peoples R China

[2] NW Univ Xian, Dept Chem Engn, Xian 710069, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 17期

关键词：

D O I：

10.1081/SCC-100105388

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general and practical route for the moderate yield oxidative conversion of readily accessible 1,4-dihydropyridines (1,4-DHPs) to the corresponding pyridines was described using a relatively benign oxidant, i.e. ferric chloride hexahydrate (FeCl3. 6H(2)O). The reaction was carried out under mild and convenient condition. However, oxidation of 4-isopropyl-1,4-DHP lb with FeCl3. 6H(2)O afforded the dealkylated pyridine 2a.

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页码：2625 / 2630

页数：6

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