Calculation of enantiomer ratio and equilibrium constants in biocatalytic ping-pong bi-bi resolutions

被引：36

作者：

Anthonsen, HW

Hoff, BH

Anthonsen, T

机构：

[1] Department of Chemistry, Rosenborg, Norwegian Univ. of Sci./Technology

[2] Department of Biochemistry, University of Wisconsin, 420 Henry Mall, Madison

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 09期

关键词：

D O I：

10.1016/0957-4166(96)00338-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A computer program for the determination of kinetic and thermodynamic parameters in biocatalytic ping-pong bi-bi resolutions has been developed. The program uses enantiomeric excesses of both product (ee(p)) and remaining substrate (ee(s)) measured at more than one conversion(xi), and determines both the equilibrium constant K-eq, the enantiomer ratio E and the selectivity factor alpha. The program has been tested for transesterification of 1-phenoxy-2-propanol using different excesses of acyl donor. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：2633 / 2638

页数：6

共 7 条

[1] A simple method for calculating enantiomer ratio and equilibrium constants in biocatalytic resolutions [J].