INTERFERON-GAMMA RELEASE ASSAY PERFORMANCE FOR DIAGNOSING TUBERCULOSIS DISEASE IN 0-TO 5-YEAR-OLD CHILDREN

被引：30

作者：

Debord, Camille ^{[1
]}

De lauzanne, Agathe ^{[2
]}

Gourgouillon, Nadege ^{[1
]}

Guerin-El Khourouj, Valerie ^{[1
]}

Pedron, Beatrice ^{[1
]}

Gaudelus, Joel ^{[3
,4
]}

Faye, Albert ^{[2
]}

Sterkers, Ghislaine ^{[1
]}

机构：

[1] Univ Paris 07, Hop Robert Debre, AP HP, Immunol Lab, F-75019 Paris, France

[2] Univ Paris 07, Hop Robert Debre, AP HP, Dept Pediat, F-75019 Paris, France

[3] Jean Verdier Hosp, AP HP, Dept Pediat, Bondy, France

[4] Univ Paris 13, Paris, France

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2011年 / 30卷 / 11期

关键词：

children; tuberculosis; interferon-gamma; release assay; SKIN-TEST; INFECTION; AGE;

D O I：

10.1097/INF.0b013e3182272227

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

QuantiFERON-TB Gold In-Tube performance was evaluated in 19 French immunocompetent children (0.29-5.36 years; median: 1.52) with active tuberculosis. The rate of indeterminates results was 0/19 and the rates of positivity were 6/10 and 9/9 in <2 and 2- to 5-year-old children, respectively. QuantiFERON-TB Gold In-Tube in association with tuberculin skin test could improve diagnosis of tuberculosis even in young children.

引用

收藏

页码：995 / 997

页数：3

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