Acute electroretinographic changes during Sildenafil (Viagra) treatment for erectile dysfunction - Sildenafil-induced ERG changes

被引：15

作者：

Gabrieli, CB

Regine, F

Vingolo, EM

Rispoli, E

Isidori, A

机构：

[1] Univ Roma La Sapienza, Dept Ophthalmol, Androl Sect, I-00161 Rome, Italy

[2] Univ Roma La Sapienza, Dept Clin Pathophysiol, Androl Sect, I-00161 Rome, Italy

来源：

DOCUMENTA OPHTHALMOLOGICA | 2003年 / 107卷 / 02期

关键词：

Sildenafil; ERG; Naka-Rushton;

D O I：

10.1023/A:1026271404384

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The authors describe their findings on 12 subjects who were treated with 50 mg of Sildenafil (Viagra) and underwent ERG measurements prior to and 1 hour after ingestion. The Naka-Rushton equation was used to describe the b-wave luminance-response function of the scotopic ERG. Statistically significant differences were noted in the V-max and K values. Sildenafil ingestion resulted in an increase in V-max (higher rod response to light stimuli) and a decrease in K (higher sensitivity).

引用

页码：111 / 114

页数：4

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