Erythropoietin and the endothelium - a promising link?

被引：15

作者：

Fliser, D. ^{[1
]}

Bahlmann, F. H. ^{[1
]}

机构：

[1] Univ Saarland, Med Ctr, Dept Renal & Hypertens Dis, D-6650 Homburg, Germany

来源：

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 2008年 / 38卷 / 07期

关键词：

AKT activation; erythropoietin (EPO); nitric oxide; vascular protection;

D O I：

10.1111/j.1365-2362.2008.01968.x

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

The major physiological function of erythropoietin (EPO) is thought to be the induction of erythropoiesis. However, a growing body of evidence indicates that EPO as well as recombinant human erythropoietin (rHuEPO) and its analogues have tissue-protective effects and prevent tissue damage during ischaemia. This mini review summarizes the present knowledge on protective vascular effects of EPO and discusses the potential underlying mechanisms.

引用

页码：457 / 461

页数：5

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