Lipid-laden macrophage infiltration of human adenocarcinoma in vivo associated with taxol and GCSF treatment

被引：3

作者：

Abramson, N

Castro, S

Goldstein, JD

机构：

[1] Baptist Regional Cancer Institute, Baptist Medical Center, Jacksonville, FL

[2] Baptist Regional Cancer Institute, Jacksonville, FL 32207

来源：

CANCER INVESTIGATION | 1997年 / 15卷 / 01期

关键词：

macrophage; chemotherapy; adenocarcinoma; taxol; GCSF;

D O I：

10.3109/07357909709018913

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This brief report illustrates the presence of lipid-laden macrophages in proximity to metastatic adenocarcinoma cells within fire bone marrow of a patient receiving taxol and GCSF therapy. The pathophysiological mechanism is uncertain. Taxol, which is associated with macrophage function in vitro, may have been responsible for the recruitment of macrophages in this patient. GCSF could have contributed as well; however; GCSF usually has little effect on monocytes and macrophages.

引用

页码：18 / 22

页数：5

共 13 条

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[2]

DING AH, 1992, J IMMUNOL, V148, P2853

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