Signal transduction mediated by artificial cell-surface receptors: activation of lactate dehydrogenase triggered by molecular recognition and phase reorganization of bile acid derivatives embedded in a synthetic bilayer membrane

被引：59

作者：

Kikuchi, J ^{[1
]}

Ariga, K ^{[1
]}

Ikeda, K ^{[1
]}

机构：

[1] Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 6300101, Japan

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 06期

关键词：

D O I：

10.1039/a900083f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A bile acid derivative, N-(2-aminoethyl)-5 beta-cholan-24-amide, acts as an artificial cell-surface receptor capable of activating lactate dehydrogenase by performing double signal recognition and phase reorganization in a synthetic bilayer membrane.

引用

页码：547 / 548

页数：2

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