Steroidal glycosides from the seeds of Hyoscyamus niger L.

被引:1
作者
Lunga, Irina [2 ]
Bassarello, Carla [1 ]
Kintia, Pavel [2 ]
Shvets, Stepan [2 ]
Piacente, Sonia [1 ]
Pizza, Cosimo [1 ]
机构
[1] Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Salerno, Italy
[2] Moldavian Acad Sci, Inst Genet & Physiol Plants, Kishinev 2004, Moldova
关键词
Hyoscyamus niger L; Solanaceae; furostanol glycosides; spirostanol glycosides;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 [药物化学];
摘要
The investigation of the steroidal glycosides of the seeds of Hyoscyamus niger L. led to the isolation of two new spirostane saponins (2, 6) together with seven known glycosides with either furostane or spirostane aglycones . On the basis of chemical and spectroscopic evidence, the structures of 2 and 6 were elucidated as (25R)-5 alpha-spirostan-3 beta-ol 3-O-beta-D-glucopyranosyl-(1 -> 3)-beta-D-galactopyranoside (2) and (25R)-5 alpha-spirostan-3 beta-ol 3-O-beta-D-glucopyranosyl-(1 -> 3)-[beta-D-glucopyranosyl-(1 -> 2)]-beta-D-galactopyranoside (6). The given compounds have been found for the first time in the genus Hyoscyamus.
引用
收藏
页码:731 / 734
页数:4
相关论文
共 14 条
[1]
[Anonymous], 2000, PHARMACOPOEIA PEOPLE, V1, P41
[2]
ASHRAF M, 1985, Journal of Pharmacy (Lahore), V6, P55
[3]
Duke J.A., 1985, CRC HDB MED HERBS, P240
[4]
Gutsu E.V., 1987, KHIMIA PRIRODNYKH SO, V2, P242
[5]
Imai S, 1967, TAKEDA KENKYUSHO NEN, V26, P76
[6]
Kirtikar KR, 1975, INDIAN MED PLANTS, V3
[7]
Saponins in Tribulus terrestris – Chemistry and Bioactivity [J].
I. Kostova ;
D. Dinchev .
Phytochemistry Reviews, 2005, 4 (2-3) :111-137
[8]
Lignanamides and nonalkaloidal components of Hyoscyamus niger seeds [J].
Ma, CY ;
Liu, WK ;
Che, CT .
JOURNAL OF NATURAL PRODUCTS, 2002, 65 (02) :206-209
[9]
Withanolides from Hyoscyamus niger seeds [J].
Ma, CY ;
Williams, ID ;
Che, CT .
JOURNAL OF NATURAL PRODUCTS, 1999, 62 (10) :1445-1447
[10]
STUDIES ON THE CONSTITUENTS OF SOLANUM PLANTS .1. ON THE CONSTITUENTS OF THE STEM PARTS OF SOLANUM-LYRATUM THUNB [J].
MURAKAMI, K ;
SAIJO, R ;
NOHARA, T ;
TOMIMATSU, T .
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1981, 101 (03) :275-279