Heparan sulfate:: lessons from knockout mice

被引:142
作者
Forsberg, E [1 ]
Kjellén, L [1 ]
机构
[1] Uppsala Univ, Dept Med Biochem & Microbiol, Ctr Biomed, SE-75123 Uppsala, Sweden
关键词
D O I
10.1172/JCI200113561
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
[No abstract available]
引用
收藏
页码:175 / 180
页数:6
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共 45 条
[1]  
AIKAWA J, 2000, IN PRESS J BIOL CHEM
[2]   Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice [J].
Alexander, CM ;
Reichsman, F ;
Hinkes, MT ;
Lincecum, J ;
Becker, KA ;
Cumberledge, S ;
Bernfield, M .
NATURE GENETICS, 2000, 25 (03) :329-332
[3]   Perlecan is essential for cartilage and cephalic development [J].
Arikawa-Hirasawa, E ;
Watanabe, H ;
Takami, H ;
Hassell, JR ;
Yamada, Y .
NATURE GENETICS, 1999, 23 (03) :354-358
[4]   Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion [J].
Bellaiche, Y ;
The, I ;
Perrimon, N .
NATURE, 1998, 394 (6688) :85-88
[5]   Functions of cell surface heparan sulfate proteoglycans [J].
Bernfield, M ;
Götte, M ;
Park, PW ;
Reizes, O ;
Fitzgerald, ML ;
Lincecum, J ;
Zako, M .
ANNUAL REVIEW OF BIOCHEMISTRY, 1999, 68 :729-777
[6]   Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase [J].
Bullock, SL ;
Fletcher, JM ;
Beddington, RSP ;
Wilson, VA .
GENES & DEVELOPMENT, 1998, 12 (12) :1894-1906
[7]  
Cano-Gauci DF, 1999, J CELL BIOL, V146, P255
[8]   Perlecan maintains the integrity of cartilage and some basement membranes [J].
Costell, M ;
Gustafsson, E ;
Aszódi, A ;
Mörgelin, M ;
Bloch, W ;
Hunziker, E ;
Addicks, K ;
Timpl, R ;
Fässler, R .
JOURNAL OF CELL BIOLOGY, 1999, 147 (05) :1109-1122
[9]   Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice [J].
Dono, R ;
Texido, G ;
Dussel, R ;
Ehmke, H ;
Zeller, R .
EMBO JOURNAL, 1998, 17 (15) :4213-4225
[10]  
DUNCAN G, 2001, IN PRESS J CLIN INVE