Intramolecular cyclopropanation reactions en route to novel P-heterocycles

被引：22

作者：

Hanson, PR ^{[1
]}

Sprott, KT ^{[1
]}

Wrobleski, AD ^{[1
]}

机构：

[1] Univ Kansas, Dept Chem, Lawrence, KS 66045 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 08期

关键词：

D O I：

10.1016/S0040-4039(99)00023-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first examples of intramolecular cyclopropanation reactions on a phosphonate template catalyzed by Rh-2(OAc)(4) are described. These reactions proceed in excellent yield and give mixtures of the P-heterocycles cis-2a-d and trans-2a-d with moderate levels of diastereoselectivity. The diastereoselectivity of this transformation is dependent upon the size of the alkyl group R contained in the alkyl alpha-diazodiallylphosphonoacetate starting materials 1a-d. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：1455 / 1458

页数：4

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