Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

被引：10

作者：

Hershkovitz, E

Leiberman, E

Limony, Y

Shany, S

Phillip, M

机构：

[1] SOROKA MED UNIV CTR,PEDIAT DIAGNOST & THERAPEUT CTR,IL-84101 BEER SHEVA,ISRAEL

[2] SOROKA MED UNIV CTR,CLIN BIOCHEM LABS,IL-84101 BEER SHEVA,ISRAEL

来源：

HORMONE RESEARCH | 1996年 / 46卷 / 01期

关键词：

growth hormone; short children; lipoprotein (a);

D O I：

10.1159/000184975

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 pears. GH increased serum Lp(a) concentrations in all the children studied, An increase to 107+/-5, 161.6+/-14.7 and 152.5+/-8.5% (mean+/-SE) of baseline levels was observed after 2 (p=NS), 6 (p <0.01) and 12 weeks (p <0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

引用

收藏

页码：38 / 40

页数：3

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