Peripheral Adaptation Mechanisms in Physical Training and Cardiac Rehabilitation: The Case of a Patient Supported by a Cardiowest Total Artificial Heart

被引：10

作者：

Bellotto, Fabio ^{[1
,2
]}

Compostella, Leonida ^{[1
]}

Agostoni, Piergiuseppe ^{[3
]}

Torregrossa, Gianluca ^{[2
]}

Setzu, Tiziana ^{[1
]}

Gambino, Antonio ^{[2
]}

Russo, Nicola ^{[1
,2
]}

Feltrin, Giuseppe ^{[2
]}

Tarzia, Vincenzo ^{[2
]}

Gerosa, Gino ^{[2
]}

机构：

[1] Ist Codivilla Putti, I-32043 Cortina Dampezzo, BL, Italy

[2] Univ Padua, Dept Cardiac Thorac & Vasc Sci, Padua, Italy

[3] Univ Milan, IRCSS, Dept Cardiovasc Sci, Monzino Cardiol Ctr, Milan, Italy

来源：

JOURNAL OF CARDIAC FAILURE | 2011年 / 17卷 / 08期

关键词：

Congestive heart failure; cardiopulmonary exercise testing; SKELETAL-MUSCLE; ENDOTHELIAL DYSFUNCTION; EXERCISE INTOLERANCE; FAILURE MECHANISMS; CONTROLLED-TRIAL; CAPACITY; DIAGNOSIS; PERFORMANCE; GUIDELINES; MANAGEMENT;

D O I：

10.1016/j.cardfail.2011.04.006

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Background: The benefits of exercise training in patients with chronic heart failure (CHF) are due to a combination of cardiac and peripheral adaptations. Separating these 2 components is normally impossible, except for patients implanted with total artificial heart (TAR), where cardiac adaptation cannot occur. Methods and Results: We report the case of a patient implanted with a CardioWest-TAH who underwent a comprehensive strength and endurance training program and was evaluated by repeated peak cardiopulmonary exercise tests. The patient experienced a 24% increase of peak oxygen consumption and an improvement in recovery kinetics during the training period of 29 months. Conclusion: This unique situation of a patient with a TAR, and therefore a fixed peak cardiac output, allows us to isolate training-induced changes in the periphery, that suggest greater oxygen extraction and more efficient metabolic gas kinetics during the exercise and recovery phases. (J Cardiac Fail 2011;17:670-675)

引用

页码：670 / 675

页数：6

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