Development of organic-dye-doped silica nanoparticles in a reverse microemulsion

被引：370

作者：

Zhao, XJ

Bagwe, RP

Tan, WH ^{[1
]}

机构：

[1] Univ Florida, Ctr Res Bio Nano Interface, Dept Chem, Gainesville, FL 32611 USA

[2] Univ Florida, McKnight Brain Inst, Gainesville, FL 32611 USA

来源：

ADVANCED MATERIALS | 2004年 / 16卷 / 02期

关键词：

D O I：

10.1002/adma.200305622

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new synthesis method to produce various organic-dye-doped silica nanoparticles using a reverse microemulsion has been developed. These nanoparticles show extremely high fluorescent signals (see Figure), excellent photostability, and size uniformity and tenability. These dye-doped silica nanoparticles can be used for various applications, especially in ultra-sensitive bioanalysis and in biomedical monitoring.

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页码：173 / +

页数：5

相关论文

共 25 条

[1] Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection [J].

Cao, YWC ;

Jin, RC ;

Mirkin, CA .

SCIENCE, 2002, 297 (5586) :1536-1540

[2] Quantum dot bioconjugates for ultrasensitive nonisotopic detection [J].

Chan, WCW ;

Nie, SM .

SCIENCE, 1998, 281 (5385) :2016-2018

[3] Self-assembly of monolayers of cadmium selenide nanocrystals with dual color emission [J].

Chen, CC ;

Yet, CP ;

Wang, HN ;

Chao, CY .

LANGMUIR, 1999, 15 (20) :6845-6850

[4] Nanoparticle-cored dendrimers: Synthesis and characterization [J].

Gopidas, KR ;

Whitesell, JK ;

Fox, MA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (21) :6491-6502

[5]

HAUGLAND RP, 2002, HDB FLUORESCENT PROB, P581

[6] Bioconjugated nanoparticles for DNA protection from cleavage [J].

He, XX ;

Wang, KM ;

Tan, WH ;

Liu, B ;

Lin, X ;

He, CM ;

Li, D ;

Huang, SS ;

Li, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (24) :7168-7169

[7] Optical patterning and photochemical fixation of polymer nanoparticles on glass substrates (vol 78, pg 2566, 2001) [J].

Ito, S ;

Yoshikawa, H ;

Masuhara, H .

APPLIED PHYSICS LETTERS, 2001, 78 (25) :4046-4046

[8] Preparation and characterization of coenzyme Q10-loaded PMMA nanoparticles by a new emulsification process based on microfluidization [J].

Kwon, SS ;

Nam, YS ;

Lee, JS ;

Ku, BS ;

Han, SH ;

Lee, JY ;

Chang, IS .

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2002, 210 (01) :95-104

[9] Synthesis and properties of water-soluble gold colloids covalently derivatized with neutral polymer monolayers [J].

Mangeney, C ;

Ferrage, F ;

Aujard, I ;

Marchi-Artzner, V ;

Jullien, L ;

Ouari, O ;

Rékai, ED ;

Laschewsky, A ;

Vikholm, I ;

Sadowski, JW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (20) :5811-5821

[10] Programmed assembly of DNA functionalized quantum dots [J].

Mitchell, GP ;

Mirkin, CA ;

Letsinger, RL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (35) :8122-8123