The evolution of noncoding DNA: how much junk, how much func?

被引：26

作者：

Castillo-Davis, CI ^{[1
]}

机构：

[1] Harvard Univ, Dept Stat, Cambridge, MA 02138 USA

来源：

TRENDS IN GENETICS | 2005年 / 21卷 / 10期

关键词：

D O I：

10.1016/j.tig.2005.08.001

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Comparative sequence analysis on a genomic scale has opened the door for the systematic analysis of cis-acting regulatory DNA. It is now possible to begin to answer basic questions such as, how much meaningful noncoding sequence is in the genome? How strong is natural selection on functional noncoding sequences in different species? Two recent articles have capitalized on the comparative genomic approach in an attempt to answer these questions with surprising results.

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页码：533 / 536

页数：4

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