Systems of biochemical reactions from the point of view of a semigrand partition function

被引：3

作者：

Alberty, RA ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

BIOPHYSICAL CHEMISTRY | 2001年 / 93卷 / 01期

关键词：

semigrand partition function; transformed Gibbs energy; Legendre transform; glycolysis; equilibrium composition;

D O I：

10.1016/S0301-4622(01)00202-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Semigrand partition functions contain all the thermodynamic information on reaction systems. When they are written for systems at specified pH, they yield the transformed Gibbs energy G' of the system and the thermodynamic properties that can be calculated from G'. When they are written for systems at specified pH and specified concentrations of coenzymes, they yield the further transformed Gibbs energy G " and properties that can be calculated from G ". This is illustrated by considering: (1) a reactant that is a weak monoprotic acid at a specified pH; (2) a reaction between two pseudoisomer groups at a specified pH; and (3) the first five reactions of glycolysis. Equilibrium compositions in glycolysis are calculated at pH 7 and different steady-state concentrations of ATP and ADP. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：1 / 10

页数：10

共 18 条

[1] Calculation of standard formation properties of species from standard transformed formation properties of reactants in biochemical reactions at specified pH [J].

Alberty, RA .

JOURNAL OF PHYSICAL CHEMISTRY B, 1999, 103 (01) :261-265

[2] Effect of pH on protein-ligand equilibria [J].

Alberty, RA .

JOURNAL OF PHYSICAL CHEMISTRY B, 2000, 104 (42) :9929-9934

[3] EQUILIBRIUM CALCULATIONS ON SYSTEMS OF BIOCHEMICAL REACTIONS AT SPECIFIED PH AND PMG [J].

ALBERTY, RA .

BIOPHYSICAL CHEMISTRY, 1992, 42 (02) :117-131

[4] Calculation of equilibrium compositions of large systems of biochemical reactions [J].

Alberty, RA .

JOURNAL OF PHYSICAL CHEMISTRY B, 2000, 104 (19) :4807-4814

[5] Calculation of standard transformed Gibbs energies and standard transformed enthalpies of biochemical reactants [J].

Alberty, RA .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1998, 353 (01) :116-130

[6] Calculation of standard transformed formation properties of biochemical reactants and standard apparent reduction potentials of half reactions [J].

Alberty, RA .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1998, 358 (01) :25-39

[7] LEVELS OF THERMODYNAMIC TREATMENT OF BIOCHEMICAL REACTION SYSTEMS [J].

ALBERTY, RA .

BIOPHYSICAL JOURNAL, 1993, 65 (03) :1243-1254

[8] CALCULATION OF TRANSFORMED THERMODYNAMIC PROPERTIES OF BIOCHEMICAL REACTANTS AT SPECIFIED PH AND PMG [J].

ALBERTY, RA .

BIOPHYSICAL CHEMISTRY, 1992, 43 (03) :239-254

[9] Use of the matrix form of the fundamental equations for transformed gibbs energies of biochemical reaction systems at three levels [J].

Alberty, RA .

JOURNAL OF PHYSICAL CHEMISTRY B, 2000, 104 (03) :650-657

[10] IDENTIFICATION OF PRINCIPAL EQUILIBRIA IN COMPLEX-SYSTEMS WITH LINEAR-PROGRAMMING [J].

ALBERTY, RA .

INDUSTRIAL & ENGINEERING CHEMISTRY FUNDAMENTALS, 1983, 22 (02) :216-219

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