Specific photodissociation of peptides with multi-stage mass spectrometry

被引：65

作者：

Tabarin, T

Antoine, R

Broyer, M

Dugourd, P

机构：

[1] Univ Lyon 1, Spectrometrie Ion & Mol Lab, UMR 5579, F-69622 Villeurbanne, France

[2] CNRS, UMR 5579, Spectrometrie Ion & Mol Lab, F-69622 Villeurbanne, France

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2005年 / 19卷 / 20期

关键词：

D O I：

10.1002/rcm.2124

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We report collision-induced dissociation (CID) and laser-induced dissociation (LID) performed at different wavelengths between 220 and 280 nm of the peptides leucine-enkephalin (protonated) and gramicidin A (sodiated). Hydrogen-atom losses and side-chain cleavages were observed in LID experiments. These losses depend on the laser wavelength and lead to the formation of radical ions. The fragmentations of these radicals, which are not observed in CID experiments, were investigated in multi-stage mass spectrometry experiments. Copyright (C) 2005 John Wiley & Sons, Ltd.

引用

页码：2883 / 2892

页数：10

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