Evolution of translational initiation: new insights from the archaea

被引：90

作者：

Londei, P

机构：

[1] Univ Roma La Sapienza, Dpt Biotecnol Cellulari & Ematol, I-00161 Rome, Italy

[2] Univ Bari, Dipartimento Biochim Med & Biol Med, I-70124 Bari, Italy

来源：

FEMS MICROBIOLOGY REVIEWS | 2005年 / 29卷 / 02期

关键词：

archaea; leaderless mRNA; translation initiation; translation initiation factors; last universal common ancestor;

D O I：

10.1016/j.femsre.2004.10.002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Recent in silico and experimental data have shed new light on the mechanism and components of translational initiation in archaea. The available data about the structure of archaeal mRNAs, mRNA/ribosome interaction and archaeal translation initiation factors are reviewed and analyzed in the conceptual framework of the evolution of translational initiation. A model of the initiation step of translation in the Last Universal Common Ancestor of extant cells is presented and discussed. (c) 2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：185 / 200

页数：16

共 77 条

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