Rapid three-dimensional passive rotation micromixer using the breakup process

被引:116
作者
Park, SJ
Kim, JK
Park, J
Chung, S
Chung, C
Chang, JK
机构
[1] Seoul Natl Univ, Sch Mech & Aerosp Engn, Seoul 151742, South Korea
[2] Digital Bio Technol Co, Inst Adv Machinery & Design, Seoul 151742, South Korea
[3] Seoul Natl Univ, Sch Elect Engn & Comp Sci, Seoul 151744, South Korea
关键词
D O I
10.1088/0960-1317/14/1/302
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Stretching and folding, diffusion, and breakup are three basic processes that occur while mixing fluids. Although stretching and folding the interface of two fluids by rotation enables the mixing at microscale level in both low and high Reynolds number flows, rotation is not as effective at a low Reynolds number as at a high Reynolds number. Therefore, developing a rapid micromixer for microfluidic systems that can be used at a low Reynolds number is a challenging task, because it can demonstrate the full potential of microfluidic systems in commercial markets. Here, to enhance the mixing efficiency of a micromixer based on passive rotation, we present a breakup method. The breakup method not only generates interface actively but also enhances the diffusion process at the interface. With our novel design, over 70% mixing can be achieved only after passing through a 4 mm long microchannel. In this work, the mixer was easily fabricated with polydimethylsiloxane by soft lithography and a self-aligned bonding method with methanol. We analyzed the flow in the micromixer using the computational fluid dynamics method. Also, we conducted quantitative analyses using a confocal scanning microscope and image processing.
引用
收藏
页码:6 / 14
页数:9
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