Dielectric studies of intermolecular interactions in native DNA

被引:20
作者
Bone, S
Lee, RS
Hodgson, CE
机构
[1] Institute of Molecular and Biomolecular Electronics, University of Wales, Bangor, Gwynedd LL57 1UT, Dean Street
来源
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1996年 / 1306卷 / 01期
关键词
dielectric relaxation; ion fluctuation; DNA packing;
D O I
10.1016/0167-4781(95)00232-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The concentration dependence of the high frequency dielectric dispersion exhibited by solutions of DNA and the sensitivity of this to the ionic strength of the solution are described. Dielectric data obtained are consistent with a model involving the fluctuation of counterions along short segments of the DNA chain. The concentration and ion strength dependencies are discussed in terms of intermolecular interactions which are considered responsible for the existence of structure in DNA solutions.
引用
收藏
页码:93 / 97
页数:5
相关论文
共 21 条
[1]   CONDENSATION OF DNA BY MULTIVALENT CATIONS - CONSIDERATIONS ON MECHANISM [J].
BLOOMFIELD, VA .
BIOPOLYMERS, 1991, 31 (13) :1471-1481
[2]  
BLOOMFIELD VA, 1974, PHYSICAL CHEM NUCLEI
[4]   DIELECTRIC STUDIES OF ION FLUCTUATION AND CHAIN BENDING IN NATIVE DNA [J].
BONE, S ;
SMALL, CA .
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1995, 1260 (01) :85-93
[5]   INFLUENCE OF DEFECTS ON THE ELECTROPHORETIC, THERMODYNAMIC AND DIELECTRIC-PROPERTIES OF A 21 BASE PAIR DNA IN SOLUTION [J].
BONINCONTRO, A ;
MATZEU, M ;
MAZZEI, F ;
MINOPRIO, A ;
PEDONE, F .
BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1171 (03) :288-294
[6]  
BONINCONTRO A, 1984, BIOPHYS J, V45, P495, DOI 10.1016/S0006-3495(84)84185-5
[7]  
GROSSE C, 1989, ALTA FREQ, V58, P365
[8]  
Mandel M, 1977, Ann N Y Acad Sci, V303, P74, DOI 10.1111/j.1749-6632.1977.tb55921.x