Patient adherence improves glycemic control

被引:240
作者
Rhee, MK
Slocum, W
Ziemer, DC
Culler, SD
Cook, CB
El-Kebbi, IM
Gallina, DL
Barnes, C
Phillips, LS
机构
[1] Emory Univ, Sch Med, Dept Med, Div Endocrinol & Metab, Atlanta, GA 30303 USA
[2] Ctr Chron Dis Contol & Hlth Prevent, Program Preparedness Branch, Strateg Natl Stockpile Program, Atlanta, GA USA
[3] Emory Univ, Rollins Sch Publ Hlth, Dept Hlth Policy & Management, Atlanta, GA 30322 USA
关键词
D O I
10.1177/0145721705274927
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose The purpose of this study was to assess the influence of appointment keeping and medication adherence on HbA1c. Methods A retrospective evaluation was performed in 1560 patients with type 2 diabetes who presented for a new visit to the Grady Diabetes Clinic between 1991 and 2001 and returned for a follow-up visit and HbA1c after I year of care. Appointment keeping was assessed by the number of scheduled intervening visits that were kept, and medication adherence was assessed by the percentage of visits in which self-reported diabetes medication use was as recommended at the preceding visit. Results The patients had an average age of 55 years, body mass index (BMI) of 32 kg/m(2), diabetes duration of 4.6 years, and baseline HbA1c of 9.1%. Ninety percent were African American, and 63% were female. Those who kept more intervening appointments had lower HbA1c levels after 12 months of care (7.6% with 6-7 intervening visits vs 9.7% with 0 intervening visits). Better medication adherence was also associated with lower HbA1c levels after 12 months of care (7.8% with 76%-100% adherence). After adjusting for age, gender, race, BMI, diabetes duration, and diabetes therapy in multivariate linear regression analysis, the benefits of appointment keeping and medication adherence remained significant and contributed independently; the HbA1c was 0.12% lower for every additional intervening appointment that was kept (P =.0001) and 0.34% lower for each quartile of better medication adherence (P =.0009). Conclusion Keeping more appointments and taking diabetes medications as directed were associated with substantial improvements in HbA1c. Efforts to enhance glycemic outcomes should include emphasis on these simple but critically important aspects of patient adherence.
引用
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页码:240 / 250
页数:11
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