Migraine with aura: Segregation analysis and heritability estimation

被引：13

作者：

Kalfakis, N

Panas, M

Vassilopoulos, D

MalliaraLoulakaki, S

机构：

[1] Department of Neurology, Athens (Greece) National University, Eginition Hospital

[2] Eginition Hospital, 115 28 Athens

来源：

HEADACHE | 1996年 / 36卷 / 05期

关键词：

migraine; heredity; genetics; segregation analysis;

D O I：

10.1046/j.1526-4610.1996.3605320.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A genetic study was performed in a group of 60 migraine patients and their first-degree relatives as well as in a group of sex- and age-matched controls. Segregation analysis showed that multifactorial inheritance seems to be the most probable mode of genetic transmission. Heritabilities were estimated according to the sex of probands and relatives. Our findings favor multifactorial inheritance, but the contribution of a major gene can not be excluded.

引用

页码：320 / 322

页数：3

共 11 条

[1] GENETICS OF MIGRAINE AND MIGRAINE ACCOMPAGNEE - A STUDY OF 81 CHILDREN AND THEIR FAMILIES [J].

BAIER, WK .

NEUROPEDIATRICS, 1985, 16 (02) :84-91

[2]

BAROLIN GS, 1969, FORTSCHR NEUROL P I, V37, P521

[3]

CATARCI T, 1992, PATHOL BIOL, V40, P284

[4] SEGREGATION ANALYSIS OF MIGRAINE IN 128 FAMILIES [J].

DEVOTO, M ;

LOZITO, A ;

STAFFA, G ;

DALESSANDRO, R ;

SACQUEGNA, T ;

ROMEO, G .

CEPHALALGIA, 1986, 6 (02) :101-105

[5]

EMERY AEH, 1976, METHODOLOGY MED GENE, P51

[6] FAMILIAL OCCURRENCE OF MIGRAINE HEADACHE - A STUDY OF HEREDITY [J].

GOODELL, H ;

LEWONTIN, R ;

WOLFF, HG .

AMA ARCHIVES OF NEUROLOGY AND PSYCHIATRY, 1954, 72 (03) :325-334

[7]

Headache Classification Committee of the International Headache Society, 1988, CEPHALALGIA S7, V8, P1

[8]

MERIKANGAS KR, 1990, MIGRAINE SPECTRUM ID, P40

[9]

RASKIN N, 1982, HEADACHE, P36

[10]

ROTHMAN KJ, 1986, MODERN EPIDEMIOLOGY, P107

← 1 2 →