2016 update of the EULAR recommendations for the management of early arthritis

被引：440

作者：

Combe, Bernard ^{[1
]}

Landewe, Robert ^{[2
]}

Daien, Claire I. ^{[1
]}

Hua, Charlotte ^{[1
]}

Aletaha, Daniel ^{[3
]}

Alvaro-Gracia, Jose Maria ^{[4
]}

Bakkers, Margot ^{[5
]}

Brodin, Nina ^{[6
,7
]}

Burmester, Gerd R. ^{[8
]}

Codreanu, Catalin ^{[9
]}

Conway, Richard ^{[10
]}

Dougados, Maxime ^{[11
]}

Emery, Paul ^{[12
]}

Ferraccioli, Gianfranco ^{[13
]}

Fonseca, Joao ^{[14
,15
]}

Raza, Karim ^{[16
,17
]}

Silva-Fernandez, Lucia ^{[18
]}

Smolen, Josef S. ^{[3
]}

Skingle, Diana ^{[5
]}

Szekanecz, Zoltan ^{[19
]}

Kvien, Tore K. ^{[20
]}

van der Helm-van Mil, Annette ^{[21
,22
]}

van Vollenhoven, Ronald ^{[23
]}

机构：

[1] Univ Montpellier, Lapeyronie Hosp, Dept Rheumatol, UMR 5535, Montpellier, France

[2] Amsterdam & Zuyderland Med Ctr, Amsterdam Rheumatol Ctr, Dept Clin Immunol & Rheumatol, Amsterdam, Netherlands

[3] Med Univ Vienna, Div Rheumatol, Dept Med 3, Vienna, Austria

[4] Hosp Univ Princesa, IIS IP, Serv Reumatol, Biol Therapies Unit, Madrid, Spain

[5] EULAR Standing Comm People Arthrit Rheumatism Eur, Zurich, Switzerland

[6] Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Physiotherapy, Huddinge, Sweden

[7] Danderyd Hosp, Dept Orthopaed, Stockholm, Sweden

[8] Charite, Dept Rheumatol & Clin Immunol, Berlin, Germany

[9] Univ Med & Pharm, Dept Rheumatol, Ctr Rheumat Dis, Bucharest, Romania

[10] St Vincents Univ Hosp, Dublin Acad Med Ctr, Ctr Arthrit & Rheumat Dis, Dept Rheumatol, Dublin, Ireland

[11] Paris Descartes Univ, Cochin Hosp, AP HP, Rheumatol Dept B,Fac Med, Paris, France

[12] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds NIHR Musculoskeletal Biomed Res Unit, LTHT, Leeds, W Yorkshire, England

[13] Catholic Univ, Fdn Policlin Gemelli Acad Hosp, Sch Med, Rome, Italy

[14] Hosp Santa Maria, Lisbon Acad Med Ctr, Dept Rheumatol, Lisbon, Portugal

[15] Univ Lisbon, Fac Med, Inst Med Mol, Lisbon, Portugal

[16] Univ Birmingham, Inst Inflammat & Ageing, Rheumatol Res Grp, Birmingham, W Midlands, England

[17] Sandwell & West Birmingham Hosp NHS Trust, Birmingham, W Midlands, England

[18] Complexo Hosp Univ Ferrol, Rheumatol Dept, La Coruna, Spain

[19] Univ Debrecen, Dept Rheumatol, Fac Med, Debrecen, Hungary

[20] Diakonhjemmet Hosp, Dept Rheumatol, Oslo, Norway

[21] Leiden Univ, Med Ctr, Dept Rheumatol, Leiden, Netherlands

[22] Erasmus MC, Dept Rheumatol, Rotterdam, Netherlands

[23] Acad Med Ctr, Dept Clin Immunol & Rheumatol, Amsterdam, Netherlands

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2017年 / 76卷 / 06期

关键词：

EARLY RHEUMATOID-ARTHRITIS; LOW DISEASE-ACTIVITY; RADIOGRAPHIC PROGRESSION; PSORIATIC-ARTHRITIS; RHEUMATOLOGY/EUROPEAN LEAGUE; AMERICAN-COLLEGE; CLASSIFICATION CRITERIA; CIGARETTE-SMOKING; ESPOIR COHORT; BONE EDEMA;

D O I：

10.1136/annrheumdis-2016-210602

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Objectives Since the 2007 recommendations for the management of early arthritis have been presented, considerable research has been published in the field of early arthritis, mandating an update of the 2007 European League Against Rheumatism (EULAR) recommendations for management of early arthritis. Methods In accordance with the 2014 EULAR Standardised Operating Procedures, the expert committee pursued an approach that was based on evidence in the literature and on expert opinion. The committee involved 20 rheumatologists, 2 patients and 1 healthcare professional representing 12 European countries. The group defined the focus of the expert committee and target population, formulated a definition of 'management' and selected the research questions. A systematic literature research (SLR) was performed by two fellows with the help of a skilled librarian. A set of draft recommendations was proposed on the basis of the research questions and the results of the SLR. For each recommendation, the categories of evidence were identified, the strength of recommendations was derived and the level of agreement was determined through a voting process. Results The updated recommendations comprise 3 overarching principles and 12 recommendations for managing early arthritis. The selected statements involve the recognition of arthritis, referral, diagnosis, prognostication, treatment (information, education, pharmacological and non-pharmacological interventions), monitoring and strategy. Eighteen items were identified as relevant for future research. Conclusions These recommendations provide rheumatologists, general practitioners, healthcare professionals, patients and other stakeholders with an updated EULAR consensus on the entire management of early arthritis.

引用

页码：948 / 959

页数：12

共 88 条

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