Is TNF really involved in cachexia?

被引：20

作者：

GarciaMartinez, C

Costelli, P

LopezSoriano, FJ

Argiles, JM

机构：

[1] UNIV BARCELONA,FAC BIOL,DEPT BIOCHEM & PHYSIOL,BARCELONA,SPAIN

[2] UNIV TURIN,DEPT MED & EXPT ONCOL,TURIN,ITALY

来源：

CANCER INVESTIGATION | 1997年 / 15卷 / 01期

关键词：

D O I：

10.3109/07357909709018916

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A review on the possible involvement of tumor necrosis factor-alpha (TNF) in cachexia is presented. While this cytokine is definitely linked to sepsis and tumor-associated weight loss in some experimental models, other cytokines, such as interleukin-6 (IL-6) or interferon-gamma (IFN-gamma), alone or in combination with TNF, may also play an important role irt the development of cachexia.

引用

页码：47 / 54

页数：8

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