Effects of microcystin-LR and cyanobacterial crude extracts on embryo-larval development of zebrafish (Danio rerio)

被引：131

作者：

Oberemm, A ^{[1
]}

Fastner, J ^{[1
]}

Steinberg, CEW ^{[1
]}

机构：

[1] GERMAN ENVIRONM PROTECT AGCY, INST WATER SOIL & AIR HYG, D-14191 BERLIN, GERMANY

来源：

WATER RESEARCH | 1997年 / 31卷 / 11期

关键词：

cyanobacterial toxins; Danio rerio; fish toxicity; microcystin-LR; zebrafish;

D O I：

10.1016/S0043-1354(97)00120-6

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Eggs of zebrafish (Danio rerio) were exposed to microcystin-LR at concentrations of 0.5, 5 and 50 mu g litre(-1) from blastula stage up to the end of embryonic development. No effects were observed during this period. After termination of exposure and transfer into microcystin-LR-free water, the evaluation at the end of the larval period showed decreased survival at 5 and 50 mu g litre(-1) microcystin-LR. Furthermore, concentrations of 0.5, 5 and 50 mu g litre(-1) microcystin-LR retarded larval growth. Far more pronounced effects occurred following exposure with various aqueous cyanobacterial crude extracts from field samples and batch cultures: gross malformations and high mortalities during embryonic development were observed. (C) 1997 Elsevier Science Ltd.

引用

页码：2918 / 2921

页数：4

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