Mitochondrial DNA in the oocyte and the developing embryo

被引：136

作者：

May-Panloup, Pascale ^{[1
]}

Chretien, Marie-Francoise

Malthiery, Yves

Reynier, Pascal

机构：

[1] INSERM, U694, F-49033 Angers, France

[2] CHU Angers, Dept Pathol Cellulaire & Tissulaire, Pole Biol, F-49033 Angers, France

[3] CHU Angers, Dept Biochim & Genet, Pole Biol, F-49033 Angers, France

来源：

MITOCHONDRION IN THE GERMLINE AND EARLY DEVELOPMENT | 2007年 / 77卷

关键词：

D O I：

10.1016/S0070-2153(06)77003-X

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mitochondria play a primary role in cellular energetic metabolism, homeostasis, and death. They possess their own multicopy genome, which is maternally transmitted. Mitochondria are directly involved at several levels in the reproductive process since their functional status influences the quality of oocytes and contributes to the process of fertilization and embryonic development. This chapter discusses recent findings concerning mitochondrial DNA content and its expression during oogenesis, fertilization, and early embryonic development. (c) 2007, Elsevier Inc.

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页码：51 / +

页数：34

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