Hemopoietic mechanisms in allergic airway inflammation

被引：12

作者：

Denburg, JA ^{[1
]}

Inman, MD ^{[1
]}

Sehmi, R ^{[1
]}

Uno, M ^{[1
]}

O'Byrne, PM ^{[1
]}

机构：

[1] McMaster Univ, Dept Med, Hamilton, ON L8N 3Z5, Canada

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 1998年 / 117卷 / 03期

关键词：

hemopoiesis; cytokines; eosinophils; inflammation; allergy; asthma; interleukin-5;

D O I：

10.1159/000024004

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The bone marrow actively participates in the production of IgER-positive inflammatory cells (eosinophils, basophils and mast cells), which are typically recruited to tissues in atopic individuals. Understanding the signalling between the tissue and the bone marrow at the molecular level may well open up new avenues of therapy for allergic inflammation.

引用

页码：155 / 159

页数：5

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