The impact of privacy protections on recruitment in a multicenter stroke genetics study

被引：9

作者：

Chen, DT

Worrall, BB

Brown, RD

Brott, TG

Kissela, BM

Olson, TS

Rich, SS

Meschia, JF

机构：

[1] Mayo Clin, Dept Neurol, Jacksonville, FL 32224 USA

[2] Univ Virginia, Virginia Ctr Biomed Ethics, Dept Hlth Evaluat Sci, Charlottesville, VA USA

[3] Univ Virginia, Virginia Ctr Biomed Ethics, Dept Psychiat, Charlottesville, VA USA

[4] Mayo Clin, Dept Neurol, Rochester, MN USA

[5] Mayo Clin, Mayo Alliance Clin Trials, Rochester, MN USA

[6] Univ Cincinnati, Dept Neurol, Cincinnati, OH USA

[7] Wake Forest Univ, Sch Med, Dept Publ Hlth Sci, Winston Salem, NC 27109 USA

来源：

NEUROLOGY | 2005年 / 64卷 / 04期

关键词：

FAMILY MEMBERS; QUESTIONNAIRE;

D O I：

10.1212/01.WNL.0000152042.07414.CC

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors reviewed the recruitment of stroke-affected sibling pairs using a letter-based, proband-initiated contact strategy. The authors randomly sampled 99 proband enrollment forms (Phase 1) and randomly sampled 50 sibling reply cards (Phase 2). The sibling response rate was 30.6%, for a pedigree response rate of 58%. Of the siblings who replied, 96% authorized further contact. Median time from proband enrollment to pedigree DNA banking, which required 3+ probands, was 134 days.

引用

页码：721 / 724

页数：4

共 9 条

[1] Protecting the privacy of family members in survey and pedigree research [J].