The genome of the domesticated apple (Malus x domestica Borkh.)

被引：1648

作者：

Velasco, Riccardo ^{[1
,3
]}

Zharkikh, Andrey ^{[2
]}

Affourtit, Jason ^{[4
]}

Dhingra, Amit

Cestaro, Alessandro ^{[1
,3
]}

Kalyanaraman, Ananth ^{[6
]}

Fontana, Paolo ^{[1
,3
]}

Bhatnagar, Satish K. ^{[2
]}

Troggio, Michela ^{[1
,3
]}

Pruss, Dmitry ^{[2
]}

Salvi, Silvio ^{[1
,3
,7
]}

Pindo, Massimo ^{[1
,3
]}

Baldi, Paolo ^{[1
,3
]}

Castelletti, Sara ^{[1
,3
]}

Cavaiuolo, Marina ^{[1
,3
]}

Coppola, Giuseppina ^{[1
,3
]}

Costa, Fabrizio ^{[1
,3
]}

Cova, Valentina ^{[1
,3
]}

Dal Ri, Antonio ^{[1
,3
]}

Goremykin, Vadim ^{[1
,3
]}

Komjanc, Matteo ^{[1
,3
]}

Longhi, Sara ^{[1
,3
]}

Magnago, Pierluigi ^{[1
,3
]}

Malacarne, Giulia ^{[1
,3
]}

Malnoy, Mickael ^{[1
,3
]}

Micheletti, Diego ^{[1
,3
]}

Moretto, Marco ^{[1
,3
]}

Perazzolli, Michele ^{[1
,3
]}

Si-Ammour, Azeddine ^{[1
,3
]}

Vezzulli, Silvia ^{[1
,3
]}

Zini, Elena ^{[1
,3
]}

Eldredge, Glenn ^{[2
]}

Fitzgerald, Lisa M. ^{[2
]}

Gutin, Natalia ^{[2
]}

Lanchbury, Jerry ^{[2
]}

Macalma, Teresita ^{[2
]}

Mitchell, Jeff T. ^{[2
]}

Reid, Julia ^{[2
]}

Wardell, Bryan ^{[2
]}

Kodira, Chinnappa ^{[4
]}

Chen, Zhoutao ^{[4
]}

Desany, Brian ^{[4
]}

Niazi, Faheem ^{[4
]}

Palmer, Melinda ^{[4
]}

Koepke, Tyson ^{[5
]}

Jiwan, Derick ^{[5
]}

Schaeffer, Scott ^{[5
]}

Krishnan, Vandhana ^{[6
]}

Wu, Changjun ^{[6
]}

Chu, Vu T. ^{[8
]}

机构：

[1] Ist Agrario San Michele Adige Res, Trento, Italy

[2] Myriad Genet, Salt Lake City, UT USA

[3] Fdn Edmund Mach, Innovat Ctr, Trento, Italy

[4] Roche Co, Branford, CT USA

[5] Washington State Univ, Dept Hort & Landscape Architecture, Pullman, WA 99164 USA

[6] Washington State Univ, Sch Elect Engn & Comp Sci, Pullman, WA USA

[7] Univ Bologna, Dept Agroenvironm Sci & Technol, Bologna, Italy

[8] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA

[9] Amplicon Express, Pullman, WA USA

[10] Parco Tecnol Padano, Lodi, Italy

[11] Univ Milan, Dept Biomol Sci & Biotechnol, Milan, Italy

[12] Univ Milan, Dept Biol, Milan, Italy

[13] INRA, French Natl Inst Agr Res Angers Nantes, UMR1259 Genet & Hort, IFR149 QUASAV, Beaucouze, France

[14] New Zealand Inst Plant Food Res, Mt Albert Res Ctr, Auckland, New Zealand

[15] New Zealand Inst Plant Food Res, Hawkes Bay Res Ctr, Havelock N, New Zealand

[16] New Zealand Inst Plant Food Res, Palmerston N Res Ctr, Palmerston North, New Zealand

[17] Univ Padua, Padua, Italy

[18] Univ Ghent VIB, Dept Plant Syst Biol, Bioinformat & Syst Biol Div, Ghent, Belgium

[19] Univ Ghent, Dept Plant Biotechnol & Genet, Ghent, Belgium

[20] Univ Padua, Dept Biol Chem, Padua, Italy

来源：

NATURE GENETICS | 2010年 / 42卷 / 10期

基金：

美国国家卫生研究院;

关键词：

SORBITOL TRANSPORTERS; GENUS MALUS; SEQUENCE; EVOLUTION; CLASSIFICATION; GENES; FRUIT; MILL; MICROSATELLITES; IDENTIFICATION;

D O I：

10.1038/ng.654

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We report a high-quality draft genome sequence of the domesticated apple (Malus x domestica). We show that a relatively recent (> 50 million years ago) genome-wide duplication (GWD) has resulted in the transition from nine ancestral chromosomes to 17 chromosomes in the Pyreae. Traces of older GWDs partly support the monophyly of the ancestral paleohexaploidy of eudicots. Phylogenetic reconstruction of Pyreae and the genus Malus, relative to major Rosaceae taxa, identified the progenitor of the cultivated apple as M. sieversii. Expansion of gene families reported to be involved in fruit development may explain formation of the pome, a Pyreae-specific false fruit that develops by proliferation of the basal part of the sepals, the receptacle. In apple, a subclade of MADS-box genes, normally involved in flower and fruit development, is expanded to include 15 members, as are other gene families involved in Rosaceae-specific metabolism, such as transport and assimilation of sorbitol.

引用

页码：833 / +

页数：9

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