Kainic acid-induced perirhinal cortical seizures in rats

被引：10

作者：

Imamura, S

Tanaka, S

Tojo, H

Fukumoto, S

Uetsuhara, K

Kuratsu, J

Takigawa, M

机构：

[1] Kagoshima Univ, Dept Neurosurg, Fac Med, Kagoshima 890, Japan

[2] Kagoshima Univ, Fac Med, Dept Neuropsychiat, Kagoshima 890, Japan

[3] Kagoshima City Hosp, Dept Neurosurg, Kagoshima, Japan

来源：

BRAIN RESEARCH | 1998年 / 800卷 / 02期

关键词：

experimental epilepsy; kainic acid; perirhinal cortex; sensorimotor cortex; secondary generalization;

D O I：

10.1016/S0006-8993(98)00513-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Seizures induced in rats by kainic acid microinjection into the perirhinal cortex were studied electrophysiologically and behaviorally and compared with known features of seizures following kainic acid injection into the amygdala. Unlike amygdalar seizures, perirhinal cortical seizures did not generalize to become Limbic seizures but rather spread to sensorimotor cortex to become manifest as motor seizures. Perirhinal cortical seizures also required larger kainic acid doses for provocation and were briefer. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：323 / 327

页数：5

共 23 条

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[Anonymous], 1979, A Stereotaxic Atlas of the Rat Brain

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