Strong intra- and inter-continental differentiation revealed by Y chromosome SNPs M269, U106 and U152

被引：40

作者：

Cruciani, Fulvio ^{[1
]}

Trombetta, Beniamino ^{[1
]}

Antonelli, Cheyenne ^{[1
]}

Pascone, Roberto ^{[2
]}

Valesini, Guido ^{[3
]}

Scalzi, Valentina ^{[3
]}

Vona, Giuseppe ^{[4
]}

Melegh, Bela ^{[5
]}

Zagradisnik, Boris ^{[6
]}

Assum, Guenter ^{[7
]}

Efremov, Georgi D. ^{[8
]}

Sellitto, Daniele ^{[9
]}

Scozzari, Rosaria ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dipartimento Genet & Biol Mol, I-00185 Rome, Italy

[2] Univ Roma La Sapienza, Dipartimento Pediat, I-00185 Rome, Italy

[3] Univ Roma La Sapienza, Dipartimento Clin & Terapia Med, I-00185 Rome, Italy

[4] Univ Cagliari, Dipartimento Biol Sperimentale, Cagliari, Italy

[5] Univ Pecs, Dept Med Genet, Pecs, Hungary

[6] Univ Med Ctr Maribor, Med Genet Lab, Maribor, Slovenia

[7] Univ Ulm, Inst Humangenet, Ulm, Germany

[8] Macedonian Acad Sci & Arts, Res Ctr Genet Engn & Biotechnol, Skopje, Macedonia

[9] CNR, Ist Biol & Patol Mol, Rome, Italy

来源：

FORENSIC SCIENCE INTERNATIONAL-GENETICS | 2011年 / 5卷 / 03期

关键词：

Y chromosome SNPs; R1b haplogroup; Phylogeography; European populations; REFERENCE DATABASE; HAPLOTYPES; AFRICA; MICROSATELLITES; HAPLOGROUPS; GENETICS; EUROPE; ASIA;

D O I：

10.1016/j.fsigen.2010.07.006

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

More than 2700 unrelated individuals from Europe, northern Africa and western Asia were analyzed for the marker M269, which defines the Y chromosome haplogroup R1b1b2. A total of 593 subjects belonging to this haplogroup were identified and further analyzed for two SNPs, U106 and U152, which define haplogroups R1b1b2g and R1b1b2h, respectively. These haplogroups showed quite different frequency distribution patterns within Europe, with frequency peaks in northern Europe (R1b1b2g) and northern Italy/France (R1b1b2h). (C) 2010 Elsevier Ireland Ltd. All rights reserved.

引用

页码：E49 / E52

页数：4

共 24 条

[1]

[Anonymous], 1991, STAT SPATIAL DATA

[2] A Predominantly Neolithic Origin for European Paternal Lineages [J].

Balaresque, Patricia ;

Bowden, Georgina R. ;

Adams, Susan M. ;

Leung, Ho-Yee ;

King, Turi E. ;

Rosser, Zoe H. ;

Goodwin, Jane ;

Moisan, Jean-Paul ;

Richard, Christelle ;

Millward, Ann ;

Demaine, Andrew G. ;

Barbujani, Guido ;

Previdere, Carlo ;

Wilson, Ian J. ;

Tyler-Smith, Chris ;

Jobling, Mark A. .

PLOS BIOLOGY, 2010, 8 (01)

[3]

Battaglia V, 2009, EUR J HUM GENET, V17, P820, DOI 10.1038/ejhg.2008.249

[4] Forensically relevant SNP classes [J].

Budowle, Bruce ;

van Daal, Angela .

BIOTECHNIQUES, 2008, 44 (05) :603-+

[5] Excavating Y-chromosome haplotype strata in Anatolia [J].

Cinnioglu, C ;

King, R ;

Kivisild, T ;

Kalfoglu, E ;

Atasoy, S ;

Cavalleri, GL ;

Lillie, AS ;

Roseman, CC ;

Lin, AA ;

Prince, K ;

Oefner, PJ ;

Shen, PD ;

Semino, O ;

Cavalli-Sforza, LL ;

Underhill, PA .

HUMAN GENETICS, 2004, 114 (02) :127-148

[6] A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes [J].

Cruciani, F ;

Santolamazza, P ;

Shen, PD ;

Macaulay, V ;

Moral, P ;

Olckers, A ;

Modiano, D ;

Holmes, S ;

Destro-Bisol, G ;

Coia, V ;

Wallace, DC ;

Oefner, PJ ;

Torroni, A ;

Cavalli-Sforza, LL ;

Scozzari, R ;

Underhill, PA .

AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 70 (05) :1197-1214

[7] Tracing past human male movements in northern/eastern Africa and western Eurasia: New clues from Y-chromosomal haplogroups E-M78 and J-M12 [J].

Cruciani, Fulvio ;

La Fratta, Roberta ;

Trombetta, Beniamino ;

Santolamazza, Piero ;

Sellitto, Daniele ;

Colomb, Eliane Beraud ;

Dugoujon, Jean-Michel ;

Crivellaro, Federica ;

Benincasa, Tamara ;

Pascone, Roberto ;

Moral, Pedro ;

Watson, Elizabeth ;

Melegh, Bela ;

Barbujani, Guido ;

Fuselli, Silvia ;

Vona, Giuseppe ;

Zagradisnik, Boris ;

Assum, Guenter ;

Brdicka, Radim ;

Kozlov, Andrey I. ;

Efremov, Georgi D. ;

Coppa, Alfredo ;

Novelletto, Andrea ;

Scozzari, Rosaria .

MOLECULAR BIOLOGY AND EVOLUTION, 2007, 24 (06) :1300-1311

[8] Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages [J].

Cruciani, Fulvio ;

Trombetta, Beniamino ;

Sellitto, Daniele ;

Massaia, Andrea ;

Destro-Bisol, Giovanni ;

Watson, Elizabeth ;

Colomb, Eliane Beraud ;

Dugoujon, Jean-Michel ;

Moral, Pedro ;

Scozzari, Rosaria .

EUROPEAN JOURNAL OF HUMAN GENETICS, 2010, 18 (07) :800-807

[9] Arlequin (version 3.0): An integrated software package for population genetics data analysis [J].

Excoffier, Laurent ;

Laval, Guillaume ;

Schneider, Stefan .

EVOLUTIONARY BIOINFORMATICS, 2005, 1 :47-50

[10] GENETIC ABSOLUTE DATING BASED ON MICROSATELLITES AND THE ORIGIN OF MODERN HUMANS [J].

GOLDSTEIN, DB ;

LINARES, AR ;

CAVALLISFORZA, LL ;

FELDMAN, MW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (15) :6723-6727

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