Four acetylcholinesterase genes in the nematode Caenorhabditis elegans

被引：18

作者：

Arpagaus, M

Combes, D

Culetto, E

Grauso, M

Fedon, Y

Romani, R

Toutant, JP

机构：

[1] INRA, DCC, Grp Cholinesterases, F-34060 Montpellier 01, France

[2] INRA, F-06606 Antibes, France

[3] Univ Perugia, Dept Expt Med, I-06100 Perugia, Italy

来源：

JOURNAL OF PHYSIOLOGY-PARIS | 1998年 / 92卷 / 5-6期

关键词：

acetylcholinesterases; Ace genes; Caenorhabditis elegans; nematodes;

D O I：

10.1016/S0928-4257(99)80006-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Whereas a single gene encodes acetylcholinesterase (AChE) in vertebrates and most insect species, four distinct genes have been cloned and characterized in the nematode Caenorhabditis elegans. We found that ace-1 (mapped to chromosome X) is prominently expressed in muscle cells whereas ace-2 (located on chromosome I) is mainly expressed in neurons. Ace-x and ace-y genes are located in close proximity on chromosome II where they are separated by only a few hundred base pairs. The role of these two genes is still unknown. ((C) Elsevier, Paris).

引用

页码：363 / 367

页数：5

共 27 条

[1]

ARPAGAUS M, 1994, J BIOL CHEM, V269, P9957

[2] ACETYLCHOLINESTERASES OF THE NEMATODE STEINERNEMA-CARPOCAPSAE - CHARACTERIZATION OF 2 TYPES OF AMPHIPHILIC FORMS DIFFERING IN THEIR MODE OF MEMBRANE ASSOCIATION [J].