Endometrium from women with endometriosis shows increased proliferation activity

被引：71

作者：

Park, Jae Sun ^{[1
]}

Lee, Jae Hoon ^{[1
,2
]}

Kim, Miran ^{[1
]}

Chang, Hye Jin ^{[1
]}

Hwang, Kyung Joo ^{[1
]}

Chang, Ki Hong ^{[1
]}

机构：

[1] Ajou Univ, Sch Med, Dept Obstet & Gynecol, Suwon 441749, South Korea

[2] Ajou Univ, Coll Nat Sci, Dept Biol Sci, Suwon 441749, South Korea

来源：

FERTILITY AND STERILITY | 2009年 / 92卷 / 04期

关键词：

STROMAL CELLS; APOPTOSIS; BCL-2;

D O I：

10.1016/j.fertnstert.2009.04.025

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Examination of 631 infertile women, including 434 women with endometriosis and 197 without endometriosis, revealed an increasing incidence of endometrial polyps, especially in the test subjects with endometriosis, and advanced stages of endometriosis. Expression of Ki-67 and Bcl-2 proteins and MTT assay results were significantly higher in endometrium of patients with endometriosis than in patients without endometriosis. These showed increased proliferation activity and cell proliferation markers not only clinically but also pathologically. (Fertil Steril (R) 2009;92:1246-9. (C) 2009 by American Society for Reproductive Medicine.)

引用

页码：1246 / 1249

页数：4

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