Preventing HIV antiretroviral resistance through better monitoring of treatment adherence

被引:124
作者
Bangsberg, David R. [1 ,2 ]
机构
[1] Univ Calif San Francisco, Epidemiol & Prevent Intervent Ctr, Div Infect Dis, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, San Francisco Gen Hosp, Posit Hlth Program, San Francisco, CA 94143 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1086/533415
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Suboptimal adherence to antiretroviral therapy (ART) is the most common cause of viral rebound. Accurate and reliable measures of ART adherence will be needed in the transition from reactive response to proactive prevention of viral rebound in the era of chronic human immunodeficiency virus (HIV) disease management. Such tools could define individual "signature adherence patterns," which could inform regimen choice and guide behavioral intervention. Upcoming advances in adherence monitoring present opportunities to better match HIV-disease treatment strategies with individual adherence behavior.
引用
收藏
页码:S272 / S278
页数:7
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