Evaluation of a New DNA Test for Detection of Carcinogenic Human Papillomavirus

被引：26

作者：

Castle, Philip E. ^{[1
]}

Gutierrez, Erin C. ^{[2
]}

Leitch, Sharon V. ^{[2
]}

Maus, Courtney E. ^{[2
]}

McMillian, Ray A. ^{[2
]}

Nussbaumer, William A. ^{[2
]}

Vaughan, Laurence M. ^{[2
]}

Wheeler, Cosette M. ^{[3
]}

Gravitt, Patti E. ^{[4
,5
]}

Schiffman, Mark ^{[6
]}

机构：

[1] Amer Soc Clin Pathol Inst, Washington, DC 20005 USA

[2] BD Diagnost, Sparks, MD 21152 USA

[3] Univ New Mexico, Hlth Sci Ctr, Sch Med, Dept Pathol, Albuquerque, NM 87131 USA

[4] Johns Hopkins Univ, Dept Epidemiol, Baltimore, MD 21205 USA

[5] Johns Hopkins Univ, Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA

[6] NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 08期

基金：

美国国家卫生研究院;

关键词：

ATYPICAL SQUAMOUS-CELLS; RANDOMIZED-TRIAL; UNDETERMINED SIGNIFICANCE; CYTOLOGY INTERPRETATIONS; CERVICAL PRECANCER; MANAGEMENT; CANCER; WOMEN; PAPANICOLAOU; BETHESDA;

D O I：

10.1128/JCM.00422-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Using archived specimens, we evaluated a new automated real-time PCR assay (BD Diagnostics) that detects all carcinogenic human papillomaviruses (HPV) and provides HPV genotyping for seven of them, including HPV16 and HPV18, the two most carcinogenic HPV genotypes. We found comparable results with Hybrid Capture 2 (HC2) for detection of carcinogenic HPV (n = 473) and with Linear Array and Line Blot Assay (n = 371) for detection of individual HPV genotypes.

引用

页码：3029 / 3032

页数：4

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