The kamikaze approach to membrane transport

被引:240
作者
Kaback, HR [1 ]
Sahin-Tóth, M
Weinglass, AB
机构
[1] Univ Calif Los Angeles, Howard Hughes Med Inst, Dept Physiol, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Howard Hughes Med Inst, Dept Microbiol Mol Genet & Immunol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Inst Mol Biol, Los Angeles, CA 90095 USA
关键词
D O I
10.1038/35085077
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Membrane transport proteins catalyse the movement of molecules into and out of cells and organelles, but their hydrophobic and metastable nature often makes them difficult to study by traditional means. Novel approaches that have been developed and applied to one membrane transport protein, the lactose permease from Escherichia coli, are now being used to study various other membrane proteins.
引用
收藏
页码:610 / 620
页数:11
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